IL-13 and IL-17A gene polymorphisms in Japanese patients with aspirin-exacerbated respiratory disease
K Kohyama, S Abe, K Kodaira, T Yukawa… - Annals of Allergy …, 2011 - Elsevier
BACKGROUND: The role of interleukin (IL) 13 and IL-17A in aspirin-exacerbated respiratory
disease (AERD) remains unknown. OBJECTIVE: To analyze the IL-13 and IL-17A gene …
disease (AERD) remains unknown. OBJECTIVE: To analyze the IL-13 and IL-17A gene …
Thromboxane A2 receptor+ 795T> C and chemoattractant receptor-homologous molecule expressed on Th2 cells-466T> C gene polymorphisms in patients with …
K Kohyama, M Hashimoto, S Abe… - Molecular …, 2012 - spandidos-publications.com
It is well known that aspirin-exacerbated respiratory disease (AERD) is more common in
women than in men, however, whether gene polymorphisms of the thromboxane A2 receptor (…
women than in men, however, whether gene polymorphisms of the thromboxane A2 receptor (…
Arg16Gly β2-adrenergic receptor gene polymorphism in Japanese patients with aspirin-exacerbated respiratory disease
K Kohyama, S Abe, K Kodaira, T Yukawa… - International archives of …, 2011 - karger.com
Background: There has been no report that investigated β 2-adrenergic receptor (ADRB2)
gene polymorphism in patients with aspirin-exacerbated respiratory disease (AERD). Methods…
gene polymorphism in patients with aspirin-exacerbated respiratory disease (AERD). Methods…
Polymorphisms of the CYP2C19 gene in Japanese patients with aspirin-exacerbated respiratory disease
K Kohyama, S Abe, K Kodaira, T Yukawa… - Journal of Allergy and …, 2011 - jacionline.org
To the Editor: Aspirin-exacerbated respiratory disease (AERD) is a clinical syndrome
characterized by a severe asthma attack after taking aspirin, nonsteroidal anti-inflammatory drugs (…
characterized by a severe asthma attack after taking aspirin, nonsteroidal anti-inflammatory drugs (…
Phase II study of oral S-1 plus cisplatin with bevacizumab for advanced non-squamous non-small cell lung cancer
…, K Minato, K Sato, T Kazama, S Ishihara, K Kohyama… - Lung Cancer, 2013 - Elsevier
Background We conducted a phase II study to evaluate the efficacy and safety of S-1 plus
cisplatin with bevacizumab followed by maintenance bevacizumab in patients with advanced …
cisplatin with bevacizumab followed by maintenance bevacizumab in patients with advanced …
Exogenous S100A4 Protein Attenuates Bleomycin-induced Pulmonary Fibrosis in Mice by Reducing the Levels of Fibroblast Growth Factors
M Watanabe, H Hirata, M Tatewaki, K Kohyama… - 2016 - dmu.repo.nii.ac.jp
Background and objective: The calcium-binding protein S100A4 belongs to the S100 family
and is involved in fibrotic and inflammatory processes, in which tissue remodeling, cell …
and is involved in fibrotic and inflammatory processes, in which tissue remodeling, cell …
Polymorphisms of the vitamin D-binding protein (DBP) gene in Japanese patients with aspirin-exacerbated respiratory disease (AERD)
K Kohyama, A Kohyama, S Abe… - European …, 2014 - Eur Respiratory Soc
AERD is known to represent acute asthmatic attacks by means of ingestion of aspirin and
other non-steroidal anti-inflammatory drug(NSAID).Individuals with AERD are more commonly …
other non-steroidal anti-inflammatory drug(NSAID).Individuals with AERD are more commonly …
Relevance of measurement of serum periostin for diagnosing bronchial asthma and estimating its lung function abnormalities
K Kohyama, K Izuhara, A Kohyama, K Nakano… - 2012 - Eur Respiratory Soc
Bronchial asthma is diagnosed by combination of presence of characteristic symptoms and
measurement of reversibility of lung function abnormalities. Non-invasive markers such as …
measurement of reversibility of lung function abnormalities. Non-invasive markers such as …
Cultured normal human bronchial epithelial cells may produce collagen type I stimulation with TGF-b
K Kohyama, N Fueki, R Seki, A Kohyama, T Okada… - 2011 - Eur Respiratory Soc
The clinical characteristics of asthma can be logically explained by asthma-specific airway
inflammation and airway remodeling, the details of which have been recently elucidated. …
inflammation and airway remodeling, the details of which have been recently elucidated. …
Risk factors for disseminated intravascular coagulation (DIC) in patients with lung cancer
…, N Yoshida, R Souma, M Tatewaki, K Kohyama… - 2016 - Eur Respiratory Soc
Background: Treatment of DIC in lung cancer (LC) is considered more difficult than in other
lung diseases, but it has not been clarified. Aims: To elucidate the risk factors for DIC in LC, …
lung diseases, but it has not been clarified. Aims: To elucidate the risk factors for DIC in LC, …