[HTML][HTML] Schistosome egg antigens, including the glycoprotein IPSE/alpha-1, trigger the development of regulatory B cells
S Haeberlein, K Obieglo, A Ozir-Fazalalikhan… - PLoS …, 2017 - journals.plos.org
Infection with the helminth Schistosoma (S.) mansoni drives the development of interleukin (IL)-10-producing
regulatory B (Breg) cells in mice and man, which have the capacity to …
regulatory B (Breg) cells in mice and man, which have the capacity to …
[HTML][HTML] Production and glyco-engineering of immunomodulatory helminth glycoproteins in plants
RHP Wilbers, LB Westerhof, K Van Noort, K Obieglo… - Scientific reports, 2017 - nature.com
Helminth parasites control host-immune responses by secreting immunomodulatory glycoproteins.
Clinical trials and mouse model studies have demonstrated the potential of helminth-…
Clinical trials and mouse model studies have demonstrated the potential of helminth-…
[HTML][HTML] Chronic gastrointestinal nematode infection mutes immune responses to mycobacterial infection distal to the gut
K Obieglo, X Feng, VP Bollampalli… - The Journal of …, 2016 - journals.aai.org
Helminth infections have been suggested to impair the development and outcome of Th1
responses to vaccines and intracellular microorganisms. However, there are limited data …
responses to vaccines and intracellular microorganisms. However, there are limited data …
Isolated Schistosoma mansoni eggs prevent allergic airway inflammation
K Obieglo, MJ Schuijs, A Ozir‐Fazalalikhan… - Parasite …, 2018 - Wiley Online Library
Chronic helminth infection with Schistosoma (S.) mansoni protects against allergic airway
inflammation ( AAI ) in mice and is associated with reduced Th2 responses to inhaled …
inflammation ( AAI ) in mice and is associated with reduced Th2 responses to inhaled …
Schistosome-induced pulmonary B cells inhibit allergic airway inflammation and display a reduced Th2-driving function
LEPM Van der Vlugt, K Obieglo… - International journal for …, 2017 - Elsevier
Chronic schistosome infections protect against allergic airway inflammation (AAI) via the
induction of IL-10-producing splenic regulatory B (Breg) cells. Previous experiments have …
induction of IL-10-producing splenic regulatory B (Breg) cells. Previous experiments have …
Type I interferons provide additive signals for murine regulatory B cell induction by Schistosoma mansoni eggs
K Obieglo, A Costain, LM Webb… - European journal of …, 2019 - Wiley Online Library
The helminth Schistosoma mansoni (S. mansoni) induces a network of regulatory immune
cells, including interleukin (IL)‐10‐producing regulatory B cells (Bregs). However, the signals …
cells, including interleukin (IL)‐10‐producing regulatory B cells (Bregs). However, the signals …
Extract of Helicobacter pylori Ameliorates Parameters of Airway Inflammation and Goblet Cell Hyperplasia following Repeated Allergen Exposure
…, RL van den Oever, K Obieglo… - International archives of …, 2019 - karger.com
Background: An inverse relation between Helicobacter pylori infection and asthma has been
shown in epidemiological studies. Infection with H. pylori, or application of an extract of it …
shown in epidemiological studies. Infection with H. pylori, or application of an extract of it …
Microorganism-induced suppression of allergic airway disease: novel therapies on the horizon?
K Obieglo, Y van Wijck, S de Kleijn… - Expert Review of …, 2014 - Taylor & Francis
Allergic airway disease is a major global health burden, and novel treatment options are
urgently needed. Numerous epidemiological and experimental studies suggest that certain …
urgently needed. Numerous epidemiological and experimental studies suggest that certain …
[PDF][PDF] comParIson of murIne sPlenIc marGInal Zone and follIcular b cell transcrIPtomes In s. mansonI InfectIon–sImIlarItIes and dIfferences
K Obieglo, SM Kielbasa, H Mei… - … of regulatory B …, 2019 - scholarlypublications …
B cells with regulatory properties, called regulatory B (Breg) cells, are a subset of B cells with
immunomodulatory capacity. Breg cells suppress immunity in a range of different contexts, …
immunomodulatory capacity. Breg cells suppress immunity in a range of different contexts, …
[PDF][PDF] Katja Obieglo, Alice Costain, Lauren M. Webb, Arifa Ozir-Fazalalikhan, Shelia L. Brown, Andrew S. MacDonald, and Hermelijn H. Smits
AS MacDonald - Immune modulation by …, 2019 - scholarlypublications …
The helminth Schistosoma mansoni induces a network of regulatory immune cells during
the chronic phase of infection 1. The induction of B cells with regulatory properties, so called …
the chronic phase of infection 1. The induction of B cells with regulatory properties, so called …