[HTML][HTML] The crucial impact of iron deficiency definition for the course of precapillary pulmonary hypertension

…, E Rieger, B Kaessmann, M Deri, K Watzinger… - PLoS …, 2018 - journals.plos.org
Imbalances of iron homeostasis are associated with an adverse clinical outcome of pulmonary
hypertension (PH). Herein, we aimed to analyze the impact of iron deficiency (ID) in a real-…

[HTML][HTML] High expression of mTOR signaling in granulomatous lesions is not predictive for the clinical course of sarcoidosis

…, H Bacher, M Aichner, A Franchi, K Watzinger… - Respiratory …, 2021 - Elsevier
Introduction Sarcoidosis is a systemic granulomatous disease with a variable clinical presentation
and disease course. There is still no reliable biomarker available, which assists in the …

[HTML][HTML] Effects of arginine vasopressin on migration and respiratory burst activity in human leukocytes

FJ Wiedermann, K Watzinger, M Stichlberger… - Open …, 2018 - degruyter.com
Arginine vasopressin can bind to high-affinity vasopressin V1a receptors in human
leukocytes. This study aims to investigate the effects of arginine vasopressin on migration and …

Antiinflammatory properties of PAH drugs

K Watzinger, I Tancevski, T Sonnweber, J Löffler-Ragg - 2016 - Eur Respiratory Soc
In patients suffering from pulmonary arterial hypertension (PAH) elevated levels of monocyte-derived
cytokines have been described in early stage of disease. Beside vasodilatory …

Activation of the NOTCH signaling pathway stimulates migration of human B-lymphocytes

A Holzer, K Watzinger, CM Kaehler - 2015 - Eur Respiratory Soc
The NOTCH signaling pathway is required for embryonic development, cell differentiation,
and for maintenance of tissue homeostasis and stem cell function. Consequently, dysfunction …

[PDF][PDF] Role of the DSL Family on cell-cell interaction in pulmonary inflammation

K Watzinger - diglib.uibk.ac.at
1. Abstract 1 2. Zusammenfassung 2 3. Introduction 3 3.1 The Notch Signalling Pathway 3
3.1. 1 Components of the canonical pathway 3 3.1. 2 Function of Notch signalling 8 3.2 …

Pulmonary fibroblasts are affected by notch ligands in vitro

K Heugenhauser, K Watzinger, CM Kaehler - 2015 - Eur Respiratory Soc
The Notch signaling pathway is an essential pathway concerning cell communication. It
plays an important role in adult tissue homeostasis and development – in particular cell fate, …

Migration of human monocytes is stimulated by Jagged-1 and DLL-4 via the notch pathway

K Watzinger, S Desole… - European Respiratory …, 2014 - Eur Respiratory Soc
The Notch signaling pathway is a well-conserved signaling pathway. As known so far Notch
signaling is engaged in physiological processes in pulmonary hypertension (PAH). As …

Human T-lymphocytes are affected by notch ligands in vitro

T Zöggeler, K Watzinger… - European Respiratory …, 2014 - Eur Respiratory Soc
Notch signaling is believed to be engaged in the pathophysiology of lung cancer and PAH.
More recently, a significant increase of the perivascular number of T cells, cytotoxic T cells (…

Proliferation of alveolar type II pneumocytes is stimulated by Jagged-1 in vitro

R Zembacher, S Desole, C Linhart, K Watzinger… - 2012 - Eur Respiratory Soc
Notch is an ancient cell-signaling system that regulates the specification of cell fate. Recently,
Notch was found to confer antigen presenting cell function on mast cells, induce histamine …