Predicting prognosis is the key factor in selecting the proper treatment modality for patients
with spinal metastases. Therefore, various assessment systems have been designed in order …

Depression is associated with profound impairments in social and interpersonal functioning.
However, little research has addressed deficits in mentalizing capacity that may underlie …

Cancer cells constantly face a fluctuating nutrient supply and interference with adaptive
responses might be an effective therapeutic approach. It has been discovered that in the …

Particle diffusion through the intestinal mucosal barrier is restricted by the viscoelastic and
adhesive properties of the mucus gel layer, preventing their penetration to the underlying …

The objective of this study was the investigation of permeation enhancing and P-glycoprotein
(P-gp) inhibition effects of a novel thiolated chitosan, the so-named S-protected thiolated …

Background Hypoxia-induced genes are potential targets in cancer therapy. Responses to
hypoxia have been extensively studied in vitro, however, they may differ in vivo due to the …

Aim: The aim of this study was to investigate the mucus-penetrating properties of neutral
nanoparticles comprising poly(acrylic acid) (PAA) and poly(allylamine) (PAM). Materials & …

Inhibition of glycolysis has been considered as a therapeutic approach in aggressive cancers
including lung cancer. Abbreviated gluconeogenesis, mediated by phosphoenolpyruvate …

The English version of the online encyclopedia, Wikipedia, has been recently reported to be
the prominent source of online health information. However, there is little information …

Background Lung cancer is one of the most frequent cancer types and the leading cause of
cancer death worldwide. Cisplatin is a widely used chemotherapeutic for non-small cell lung …