Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: a Southwest Oncology Group/Eastern Cooperative …

…, PA Cassileth, DH Harrington, KS Theil… - Blood, The Journal …, 2000 - ashpublications.org
The associations of cytogenetics with complete remission (CR) rates, overall survival (OS),
and outcomes after CR were studied in 609 previously untreated AML patients younger than …

Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML

…, CL O'Keefe, MA Sekeres, KS Theil… - Blood, The Journal …, 2008 - ashpublications.org
Using metaphase cytogenetics (MC), chromosomal abnormalities are found in only a
proportion of patients with myelodysplastic syndrome (MDS). We hypothesized that with new …

Expression, exon-intron organization, and chromosome mapping of the human sodium iodide symporter

PA Smanik, KY Ryu, KS Theil, EL Mazzaferri… - …, 1997 - academic.oup.com
The active iodide uptake of the thyroid gland in humans is mediated by the human sodium
iodide symporter (hNIS). In this report, we show that hNIS expression was detected primarily …

Refractory anemia with ringed sideroblasts associated with marked thrombocytosis (RARS-T), another myeloproliferative condition characterized by JAK2 V617F …

…, R Tiu, G Murugesan, S Aboudola, ED Hsi, KS Theil… - Blood, 2006 - ashpublications.org
JAK2 V617F mutation recently was identified as a pathogenic factor in typical chronic
myeloproliferative diseases (CMPD). Some forms of myelodysplastic syndromes (MDS) show a …

Identification of a gene at 11q23 encoding a guanine nucleotide exchange factor: Evidence for its fusion with MLL in acute myeloid leukemia

…, ML Veronese, CM Croce, KS Theil… - Proceedings of the …, 2000 - National Acad Sciences
We have identified a gene at 11q23, telomeric to MLL, that encodes a guanine nucleotide
exchange factor (GEF). This gene is transcribed into a 9.5-kb mRNA containing a 4.6-kb ORF. …

HER-2/neu amplification and overexpression in endometrial carcinoma

CD Rolitsky, KS Theil, VR McGaughy… - International journal …, 1999 - journals.lww.com
HER-2/neu is a proto-oncogene associated with poor prognosis in women with breast and
ovarian carcinoma. The significance of HER-2/neu in endometrial carcinoma is less clearly …

HLA-DR-, CD33+, CD56+, CD16-myeloid/natural killer cell acute leukemia: a previously unrecognized form of acute leukemia potentially misdiagnosed as French …

…, DR Head, KJ Kopecky, FR Appelbaum, KS Theil… - 1994 - ashpublications.org
We have identified and characterized a previously unrecognized form of acute leukemia that
shares features of both myeloid and natural killer (NK) cells. From a consecutive series of …

Initial diagnostic workup of acute leukemia: guideline from the College of American Pathologists and the American Society of Hematology

…, RP Hasserjian, JD Rizzo, K Theil… - … of pathology & …, 2017 - meridian.allenpress.com
Context.— A complete diagnosis of acute leukemia requires knowledge of clinical information
combined with morphologic evaluation, immunophenotyping and karyotype analysis, and …

Hypoxia-inducible factors in human pulmonary arterial hypertension: a link to the intrinsic myeloid abnormalities

…, M Park, WHW Tang, JE Loyd, K Theil… - Blood, The Journal …, 2011 - ashpublications.org
Pulmonary arterial hypertension (PAH) is a proliferative vasculopathy characterized by high
circulating CD34 + CD133 + proangiogenic progenitors, and endothelial cells that have …

Comparison of cytogenetic and molecular genetic detection of t (8; 21) and inv (16) in a prospective series of adults with de novo acute myeloid leukemia: a Cancer …

…, PJ Snyder, PRK Koduru, KS Theil… - Journal of Clinical …, 2001 - ascopubs.org
PURPOSE: To prospectively compare cytogenetics and reverse transcriptase–polymerase
chain reaction (RT-PCR) for detection of t(8;21)(q22;q22) and inv(16)(p13q22)/t(16;16)(p13;…