Risk factors for chronic lung allograft dysfunction (CLAD) in the SysCLAD cohort

…, A Tissot, JD Aubert, JP Antonietti, K Botturi-Cavaillès… - 2015 - Eur Respiratory Soc
Introduction: CLAD and its phenotypes, Bronchiolitis Obliterans Syndrome (BOS) and Restrictive
Allograft Syndrome (RAS) are major causes of mortality after lung transplantation (LT). …

Modulation de l'activation lymphocytaire T dans l'asthme et le rejet chronique de transplantation pulmonaire

K Botturi-Cavailles - 2007 - theses.fr
L’activation des lymphocytes T (LT) est un évènement majeur de la réaction inflammatoire
de la pathologie bronchique. Notre travail a porté sur l’étude de l’activation des LT dans l’…

Blood mRNA and miRNA transcriptome to predict chronic lung allograft dysfunction

…, D Baron, D Reboulleau, A Tissot, K Botturi-Cavailles… - 2015 - Eur Respiratory Soc
Chronic Lung Allograft Dysfunction (CLAD) manifests as Bronchiolitis Obliterans Syndrome (BOS)
and the recently described Restrictive Allograft Syndrome (RAS). CLAD is …

Mass spectrometry methods for biomarker research for chronic lung allograft dysfunction (CLAD) in systems prediction of CLAD (SysCLAD)

…, B Toussaint, K Botturi-Cavaillès… - European …, 2014 - Eur Respiratory Soc
Background: CLAD is an irreversible and heterogeneous condition, associating Bronchiolitis
Obliterans Syndrome (BOS), and Restrictive Allograft Syndrome (RAS). RAS and early …

Immune modulation by mesenchymal stem cells in a mouse model of house dust mite allergic asthma

…, C Sagan, J Chesné, K Botturi-Cavaillès… - 2012 - Eur Respiratory Soc
Background: Mesenchymal Stem Cells (MSCs) display immunomodulatory features in
ovalbumin-induced allergic asthma models, by inducing Th1 and/or Treg polarization. However, …

Increased cytotoxic T cells, CX3CR1+, γδ and IL17+ T cells in severe asthma during exacerbation

K Botturi-Cavaillès, J Chesné, C Belleguic, C Leroyer… - 2012 - Eur Respiratory Soc
Background Asthma is a chronic inflammatory disease affecting up to 10% of the general
population. In most cases, asthma symptoms are controlled by long term treatment without side …

Chronic effects of air pollution on lung function after lung transplantation in the Systems prediction of Chronic Lung Allograft Dysfunction (SysCLAD) study

M Benmerad, R Slama, K Botturi… - European …, 2017 - Eur Respiratory Soc
An irreversible loss in lung function limits the long-term success in lung transplantation. We
evaluated the role of chronic exposure to ambient air pollution on lung function levels in lung …

Prediction of chronic lung allograft dysfunction: a systems medicine challenge

C Pison, A Magnan, K Botturi, M Seve… - European …, 2014 - Eur Respiratory Soc
The International Society for Heart and Lung Transplantation registry recorded that 3631 adult
heart-lung transplants and 39 835 adult lung transplants have been performed in centres …

[HTML][HTML] Development of a multivariate prediction model for early-onset bronchiolitis obliterans syndrome and restrictive allograft syndrome in lung transplantation

A Koutsokera, PJ Royer, JP Antonietti, A Fritz… - Frontiers in …, 2017 - frontiersin.org
Background Chronic lung allograft dysfunction and its main phenotypes, bronchiolitis obliterans
syndrome (BOS) and restrictive allograft syndrome (RAS), are major causes of mortality …

[HTML][HTML] T cells promote bronchial epithelial cell secretion of matrix metalloproteinase-9 via a CC chemokine receptor type 2 pathway: implications for chronic lung …

M Pain, PJ Royer, J Loy, A Girardeau, A Tissot… - American Journal of …, 2017 - Elsevier
Chronic lung allograft dysfunction (CLAD) is the major limitation of long-term survival after
lung transplantation. CLAD manifests as bronchiolitis obliterans syndrome (BOS) or restrictive …