User profiles for K. Shirato

Kazuya Shirato

National Insitute of Infectious Diseases
Verified email at niid.go.jp
Cited by 7143

[HTML][HTML] Wearable systems for monitoring mobility-related activities in chronic disease: a systematic review

L Allet, RH Knols, K Shirato, ED De Bruin - Sensors, 2010 - mdpi.com
The use of wearable motion sensing technology offers important advantages over
conventional methods for obtaining measures of physical activity and/or physical functioning in …

Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis

…, N Nakaya, T Sakata, K Shimada, K Shirato - The lancet, 2007 - thelancet.com
Background Epidemiological and clinical evidence suggests that an increased intake of long-chain
n-3 fatty acids protects against mortality from coronary artery disease. We aimed to …

Enhanced isolation of SARS-CoV-2 by TMPRSS2-expressing cells

S Matsuyama, N Nao, K Shirato… - Proceedings of the …, 2020 - National Acad Sciences
A novel betacoronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
which caused a large respiratory outbreak in Wuhan, China in December 2019, is currently …

Efficient activation of the severe acute respiratory syndrome coronavirus spike protein by the transmembrane protease TMPRSS2

S Matsuyama, N Nagata, K Shirato, M Kawase… - Journal of …, 2010 - Am Soc Microbiol
The distribution of the severe acute respiratory syndrome coronavirus (SARS-CoV) receptor,
an angiotensin-converting enzyme 2 (ACE2), does not strictly correlate with SARS-CoV cell …

Coronary microcirculation: physiology and pharmacology

T Komaru, H Kanatsuka, K Shirato - Pharmacology & therapeutics, 2000 - Elsevier
… The importance of ATP-sensitive K + channels in the metabolic control has been increasingly
recognized. Furthermore, many neurohumoral mediators significantly affect coronary …

[HTML][HTML] Chemosensitivity and perception of dyspnea in patients with a history of near-fatal asthma

…, G Tamura, W Hida, M Homma, K Shirato… - … England Journal of …, 1994 - Mass Medical Soc
Background Many deaths from attacks of asthma may be preventable. However, the
difficulty in preventing fatal attacks is that not all the pathophysiologic risk factors have been …

[HTML][HTML] Exercise training attenuates the dysregulated expression of adipokines and oxidative stress in white adipose tissue

T Sakurai, J Ogasawara, K Shirato, T Izawa… - … medicine and cellular …, 2017 - hindawi.com
Obesity-induced inflammatory changes in white adipose tissue (WAT), which caused
dysregulated expression of inflammation-related adipokines involving tumor necrosis factor-α and …

Simultaneous treatment of human bronchial epithelial cells with serine and cysteine protease inhibitors prevents severe acute respiratory syndrome coronavirus entry

M Kawase, K Shirato, L van der Hoek… - Journal of …, 2012 - Am Soc Microbiol
The type II transmembrane protease TMPRSS2 activates the spike (S) protein of severe
acute respiratory syndrome coronavirus (SARS-CoV) on the cell surface following receptor …

Middle East respiratory syndrome coronavirus infection mediated by the transmembrane serine protease TMPRSS2

K Shirato, M Kawase, S Matsuyama - Journal of virology, 2013 - Am Soc Microbiol
… L, K, and S in TMPRSS2-negative Vero cells. MERS-CoV cell entry was inhibited by ∼40-fold
by cathepsin L and cathepsin K … Because the cathepsin K inhibitor also inhibits cathepsin L …

Reduction in the recurrence of stroke by eicosapentaenoic acid for hypercholesterolemic patients: subanalysis of the JELIS trial

…, N Nakaya, T Sakata, K Shimada, K Shirato - Stroke, 2008 - Am Heart Assoc
Background and Purpose— The JELIS trial examined the preventive effect of eicosapentaenoic
acid (EPA) against coronary artery diseases. Hypercholesterolemic patients received …