Coeliac disease

K Lindfors, C Ciacci, K Kurppa, KEA Lundin… - Nature reviews Disease …, 2019 - nature.com
Coeliac disease is an immune-mediated enteropathy against dietary gluten present in wheat,
rye and barley and is one of the most common lifelong food-related disorders worldwide. …

[HTML][HTML] Extraintestinal manifestations of celiac disease: early detection for better long-term outcomes

P Laurikka, S Nurminen, L Kivelä, K Kurppa - Nutrients, 2018 - mdpi.com
Population-based screening studies have shown celiac disease to be one of the most
common chronic gastrointestinal diseases. Nevertheless, because of the diverse clinical …

Multiple common variants for celiac disease influencing immune gene expression

…, D Kelleher, I Korponay-Szabo, K Kurppa… - Nature …, 2010 - nature.com
We performed a second-generation genome-wide association study of 4,533 individuals with
celiac disease (cases) and 10,750 control subjects. We genotyped 113 selected SNPs with …

European society paediatric gastroenterology, hepatology and nutrition guidelines for diagnosing coeliac disease 2020

…, S Koletzko, I Korponay-Szabó, K Kurppa… - Journal of pediatric …, 2020 - journals.lww.com
Objectives: The ESPGHAN 2012 coeliac disease (CD) diagnostic guidelines aimed to guide
physicians in accurately diagnosing CD and permit omission of duodenal biopsies in …

Celiac disease and health-related quality of life

K Kurppa, P Collin, M Mäki… - Expert review of …, 2011 - Taylor & Francis
Celiac disease is a particularly common life-long disorder with a prevalence of approximately
1–2% in Western populations. In recent years the health-related quality of life has become …

Diagnosing mild enteropathy celiac disease: a randomized, controlled clinical study

K Kurppa, P Collin, M Viljamaa, K Haimila… - Gastroenterology, 2009 - Elsevier
… iron level (reference values, 50–190 μg/dL), red blood cell folate level (E-folate) (reference
values, 200–700 nmol/L), and serum vitamin B 12 level (reference values, 150–740 pmol/K). …

[PDF][PDF] Treatment-induced tumor dormancy through YAP-mediated transcriptional reprogramming of the apoptotic pathway

KJ Kurppa, Y Liu, C To, T Zhang, M Fan, A Vajdi… - Cancer cell, 2020 - cell.com
Eradicating tumor dormancy that develops following epidermal growth factor receptor (EGFR)
tyrosine kinase inhibitor (TKI) treatment of EGFR-mutant non-small cell lung cancer, is an …

High frequency of BRAF V600E mutations in ameloblastoma

KJ Kurppa, J Catón, PR Morgan… - The Journal of …, 2014 - Wiley Online Library
… Kari J Kurppa … Kari J Kurppa … line; AR performed BRAF V600E immunohistochemistry; KK
conducted all the remaining experimental work; and KK, KE and KH prepared the manuscript. …

Accuracy in diagnosis of celiac disease without biopsies in clinical practice

…, H Garnier-Lengliné, G Castillejo, K Kurppa… - Gastroenterology, 2017 - Elsevier
Background & Aims The guidelines of the European Society of Pediatric Gastroenterology,
Hepatology, and Nutrition allow for diagnosis of celiac disease without biopsies in children …

An allosteric inhibitor against the therapy-resistant mutant forms of EGFR in non-small cell lung cancer

…, PC Gokhale, Y Kobayashi, K Wahid, KJ Kurppa… - Nature cancer, 2022 - nature.com
Epidermal growth factor receptor (EGFR) therapy using small-molecule tyrosine kinase
inhibitors (TKIs) is initially efficacious in patients with EGFR-mutant lung cancer, although drug …