[HTML][HTML] The prognostic significance and value of cyclin D1, CDK4 and p16 in human breast cancer

E Peurala, P Koivunen, KM Haapasaari, R Bloigu… - Breast Cancer …, 2013 - Springer
Introduction Loss of the retinoblastoma protein tumor suppressor gene (RB) coding for a
nuclear phosphoprotein that regulates the cell cycle is found in many human cancers and …

Multiple miliary osteoma cutis is a distinct disease entity: four case reports and review of the literature

RM Myllylä, KM Haapasaari, R Palatsi… - British Journal of …, 2011 - academic.oup.com
Background: Multiple miliary osteoma cutis (MMOC) is a rare nodular skin disease characterized
by tiny bone nodules which usually form on the facial skin, typically in middle age. The …

Vimentin, zeb1 and Sip1 are up-regulated in triple-negative and basal-like breast cancers: association with an aggressive tumour phenotype

…, P Auvinen, S Kauppila, KM Haapasaari… - Breast cancer research …, 2013 - Springer
In epithelial-to-mesenchymal transition (EMT) epithelial cancer cells achieve mesenchymal
features, essentially helping them to metastasize. There is some evidence that EMT could be …

The molecular basis of glucocorticoid‐induced skin atrophy: topical glucocorticoid apparently decreases both collagen synthesis and the corresponding collagen …

…, KM Haapasaari, M Sutinen, K Tasanen - British Journal of …, 1998 - academic.oup.com
The effects of topical betamethasone‐17‐valerate on collagen propeptide levels, collagen
mRNA level, lysyl oxidase mRNA and matrix metalloproteinase (MMP)‐1 and MMP‐2 mRNA …

[HTML][HTML] 8-hydroxydeguanosine and nitrotyrosine are prognostic factors in urinary bladder carcinoma

Y Soini, KM Haapasaari, MH Vaarala… - … Journal of Clinical …, 2011 - ncbi.nlm.nih.gov
… Yokomizo A, Ono M, Nanri H, Makino Y, Ohga T, Wada M, Okamoto T, Yodoi J, Kuwano M,
Kohno K. Cellular levels of thioredoxin associated with drug sensitivity to cisplatin, mitomycin …

Nuclear Nrf2 expression is related to a poor survival in pancreatic adenocarcinoma

…, P Juvonen, V Kärjä, KM Haapasaari… - … -Research and Practice, 2014 - Elsevier
… Kärjä a , KM Haapasaari c , A. Saarela d , P. Karihtala e … Myllärniemi, K. Salmenkivi, VL
Kinnula … DR Stacy, K. Ely, PP Massion, et al. …

[HTML][HTML] Tenascin C, fibronectin, and tumor-stroma ratio in pancreatic ductal adenocarcinoma

…, V Lindholm, J Isohookana, KM Haapasaari… - Pancreas, 2019 - journals.lww.com
Objectives Pancreatic ductal adenocarcinoma (PDAC) is characterized by abundant stroma
with increased expression of tenascin C and fibronectin. Their role and tumor-stroma ratio in …

Nrf2/Keap1 pathway and expression of oxidative stress lesions 8-hydroxy-2'-deoxyguanosine and nitrotyrosine in melanoma

HR Hintsala, E Jokinen, KM Haapasaari… - Anticancer …, 2016 - ar.iiarjournals.org
Background/Aim: Increased expression and prognostic significance of major redox regulator
nuclear factor erythroid-2-related factor (Nrf2) is recognized in many cancers. Our aim was …

Biological roles and prognostic values of the epithelial–mesenchymal transition‐mediating transcription factors Twist, ZEB1 and Slug in diffuse large B‐cell lymphoma

S Lemma, P Karihtala, KM Haapasaari… - …, 2013 - Wiley Online Library
Aims: To evaluate the biological roles and prognostic significance of the epithelial–mesenchymal
transition (EMT)‐mediating transcription factors (TFs) Twist, ZEB1 and Slug in patients …

[HTML][HTML] Primary neuroendocrine breast carcinomas are associated with poor local control despite favourable biological profile: a retrospective clinical study

N Roininen, S Takala, KM Haapasaari… - BMC cancer, 2017 - Springer
Background Breast carcinomas with neuroendocrine features (NEBC) are a very rare entity
of mammary neoplasms, WHO classification of which has recently been revised. There are …