Calcium-dependent phospholipid scrambling by TMEM16F

J Suzuki, M Umeda, PJ Sims, S Nagata - Nature, 2010 - nature.com
In all animal cells, phospholipids are asymmetrically distributed between the outer and
inner leaflets of the plasma membrane 1 . This asymmetrical phospholipid distribution is …

Cardio-ankle vascular index (CAVI) as a novel indicator of arterial stiffness: theory, evidence and perspectives

…, N Hiruta, M Song, T Kurosu, J Suzuki… - … of atherosclerosis and …, 2011 - jstage.jst.go.jp
Many methods have been designed to assess arterial stiffness. Among them, pulse wave
velocity (PWV) 1-7), augmentation index8), stiffness parameter β9, 10), and carotid-femoral …

Xk-related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cells

J Suzuki, DP Denning, E Imanishi, HR Horvitz… - Science, 2013 - science.org
A classic feature of apoptotic cells is the cell-surface exposure of phosphatidylserine (PtdSer)
as an “eat me” signal for engulfment. We show that the Xk-family protein Xkr8 mediates …

[PDF][PDF] Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments

…, M Shirasawa, K Nakama, K Aokage, J Suzuki… - Cancer Cell, 2022 - cell.com
The balance of programmed death-1 (PD-1)-expressing CD8 + T cells and regulatory T (Treg)
cells in the tumor microenvironment (TME) determines the clinical efficacy of PD-1 …

[HTML][HTML] Calcium-dependent phospholipid scramblase activity of TMEM16 protein family members

J Suzuki, T Fujii, T Imao, K Ishihara, H Kuba… - Journal of Biological …, 2013 - ASBMB
Asymmetrical distribution of phospholipids between the inner and outer plasma membrane
leaflets is disrupted in various biological processes. We recently identified TMEM16F, an …

Mechanical properties and osteoconductivity of porous bioactive titanium

M Takemoto, S Fujibayashi, M Neo, J Suzuki, T Kokubo… - Biomaterials, 2005 - Elsevier
Porous bioactive titanium implants (porosity of 40%) were produced by a plasma-spray method
and subsequent chemical and thermal treatments of immersion in a 5M aqueous NaOH …

XVI eye movements from semicircular canal nerve stimulation in the cat

B Cohen, JI Suzuki, MB Bender - Annals of Otology …, 1964 - journals.sagepub.com
METHODS Because administration of even small quantities of barbiturates or other anesthetics
causes a marked decrease in facilitatory drives in vestibulo-oculomotor pathways,*'^^ …

Increased [18F]Fluorodeoxyglucose Accumulation in Right Ventricular Free Wall in Patients With Pulmonary Hypertension and the Effect of Epoprostenol

…, H Otani, M Sakuma, J Demachi, J Suzuki… - Journal of the American …, 2005 - jacc.org
Objectives : We examined whether right ventricular (RV) [ 18 F]fluorodeoxyglucose (FDG)
accumulation is increased in patients with pulmonary hypertension using gated positron …

Technological diversity of persistent innovators in Japan: Two case studies of large Japanese firms

J Suzuki, F Kodama - Research policy, 2004 - Elsevier
We have investigated two large Japanese firms with their patent data, technological
histories and product sales data of over 30 years especially in terms of intra-firm technology …

Cyclophilin A mediates vascular remodeling by promoting inflammation and vascular smooth muscle cell proliferation

K Satoh, T Matoba, J Suzuki, MR O'Dell, P Nigro… - Circulation, 2008 - Am Heart Assoc
Background— Oxidative stress, generated by excessive reactive oxygen species, promotes
cardiovascular disease. Cyclophilin A (CyPA) is a 20-kDa chaperone protein secreted from …