The APHEA 2 project investigated short-term health effects of particles in eight European cities.
In each city associations between particles with an aerodynamic diameter of less than 10 …

The LifeLines Cohort Study is a large population-based cohort study and biobank that was
established as a resource for research on complex interactions between environmental, …

In the Air Pollution and Health: A European Approach (APHEA2) project, the effects of ambient
ozone concentrations on mortality were investigated. Data were collected on daily ozone …

Background Tracking longitudinal measurements of growth and decline in lung function in
patients with persistent childhood asthma may reveal links between asthma and subsequent …

Asthma, hay fever (or allergic rhinitis) and eczema (or atopic dermatitis) often coexist in the
same individuals 1 , partly because of a shared genetic origin 2 , 3 , 4 . To identify shared risk …

Biobanks facilitate genome-wide association studies (GWASs), which have mapped genomic
loci across a range of human diseases and traits. However, most biobanks are primarily …

Pulmonary function measures reflect respiratory health and are used in the diagnosis of
chronic obstructive pulmonary disease. We tested genome-wide association with forced …

Background: Particulate air pollution is associated with increased mortality. There is a need
for European results from multicountry databases concerning cause-specific mortality to …

Several studies have reported significant health effects of air pollution even at low levels of
air pollutants, but in most of theses studies linear nonthreshold relations were assumed. We …

Characterizing genetic influences on DNA methylation (DNAm) provides an opportunity to
understand mechanisms underpinning gene regulation and disease. In the present study, we …