Background Idiopathic pulmonary fibrosis (IPF) is the most rapidly progressive and fatal fibrotic
disorder, with no curative therapies. The signal transducer and activator of transcription 3 …

Background Pulmonary hypertension (PH) is a common disorder in patients with idiopathic
pulmonary fibrosis (IPF) and portends a poor prognosis. Recent studies using vasodilators …

Background Pulmonary hypertension (PH) associated to idiopathic pulmonary fibrosis (IPF)
portends a poor prognosis. IL-11 has been implicated in fibrotic diseases, but their role on …

Background Serum KL6/mucin 1 (MUC1) has been identified as a potential biomarker in
idiopathic pulmonary fibrosis (IPF), but the role of MUC1 intracellular bioactivation in IPF is …

Sildenafil improves the 6-min walking distance in patients with idiopathic pulmonary fibrosis
(IPF) and right-sided ventricular systolic dysfunction. We analysed the previously …

Lung transplant patients present important variability in immunosuppressant blood concentrations
during the first months after transplantation. Pharmacogenetics could explain part of …

Several mucins are implicated in idiopathic pulmonary fibrosis (IPF); however, there is no
evidence regarding the role of MUC4 in the development of IPF. Here we demonstrated that …

IL-11 is linked to fibrotic diseases, but its role in pulmonary hypertension is unclear. We
examined IL-11's involvement in idiopathic pulmonary arterial hypertension (iPAH). Using …

Background Medication errors are a serious and complex problem in clinical practice, especially
in intensive care units whose patients can suffer potentially very serious consequences …

Background Despite well-known risk factors and predictive survival models, many patients
with cystic fibrosis (CF) die while on the waiting list for lung transplant. We evaluated whether …