Management of giant liver hemangiomas: an update

…, M Bieze, D Erdogan, JJTH Roelofs… - Expert review of …, 2013 - Taylor & Francis
Liver hemangiomas are the most common benign liver tumors and are usually incidental
findings. Liver hemangiomas are readily demonstrated by abdominal ultrasonography, …

[HTML][HTML] Viral presence and immunopathology in patients with lethal COVID-19: a prospective autopsy cohort study

…, HWM Niessen, CJM van Noesel, JJTH Roelofs… - The Lancet …, 2020 - thelancet.com
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) targets multiple
organs and causes severe coagulopathy. Histopathological organ changes might not only …

[HTML][HTML] The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia

…, JM Lankelma, BP Scicluna, FS e Melo, JJTH Roelofs… - Gut, 2016 - gut.bmj.com
Objective Pneumonia accounts for more deaths than any other infectious disease worldwide.
The intestinal microbiota supports local mucosal immunity and is increasingly recognised …

The role of platelets in acute kidney injury

MPB Jansen, S Florquin, JJTH Roelofs - Nature Reviews Nephrology, 2018 - nature.com
Acute kidney injury (AKI), a major public health problem associated with high mortality and
increased risk of progression towards end-stage renal disease, is characterized by the …

Assessment of future remnant liver function using hepatobiliary scintigraphy in patients undergoing major liver resection

…, KP Van Lienden, S Dinant, JJTH Roelofs… - Journal of …, 2010 - Elsevier
Background 99m Tc-mebrofenin hepatobiliary scintigraphy (HBS) was used as a quantitative
method to evaluate liver function. The aim of this study was to compare future remnant liver …

[HTML][HTML] Mechanical ventilation using non-injurious ventilation settings causes lung injury in the absence of pre-existing lung injury in healthy mice

EK Wolthuis, APJ Vlaar, G Choi, JJTH Roelofs… - Critical Care, 2009 - Springer
Introduction Mechanical ventilation (MV) may cause ventilator-induced lung injury (VILI).
Present models of VILI use exceptionally large tidal volumes, causing gross lung injury and …

Deep learning–based histopathologic assessment of kidney tissue

…, J Kers, S Florquin, JJTH Roelofs… - Journal of the …, 2019 - journals.lww.com
Background The development of deep neural networks is facilitating more advanced digital
analysis of histopathologic images. We trained a convolutional neural network for multiclass …

Thrombocytopenia impairs host defense in gram-negative pneumonia–derived sepsis in mice

…, BJA Albersen, JJTH Roelofs… - Blood, The Journal …, 2014 - ashpublications.org
Thrombocytopenia is a common finding in sepsis and associated with a worse outcome. We
used a mouse model of pneumonia-derived sepsis caused by the human pathogen …

Evaluation of conventional, dynamic contrast enhanced and diffusion weighted MRI for quantitative Crohn's disease assessment with histopathology of surgical …

…, Z Li, C Lavini, S Bipat, WA Bemelman, JJTH Roelofs… - European …, 2014 - Springer
Objectives To prospectively compare conventional MRI sequences, dynamic contrast
enhanced (DCE) MRI and diffusion weighted imaging (DWI) with histopathology of surgical …

[PDF][PDF] A tick mannose-binding lectin inhibitor interferes with the vertebrate complement cascade to enhance transmission of the lyme disease agent

…, D Wouters, M Brouwer, A Oei, JJTH Roelofs… - Cell host & …, 2011 - cell.com
The Lyme disease agent Borrelia burgdorferi is primarily transmitted to vertebrates by
Ixodes ticks. The classical and alternative complement pathways are important in Borrelia …