Ambulatory blood pressure after therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: a randomised parallel trial

…, N Crosthwaite, R Mullins, C Jenkinson, JR Stradling… - The Lancet, 2002 - thelancet.com
Background Obstructive sleep apnoea is associated with raised blood pressure. If blood
pressure can be reduced by nasal continuous positive airway pressure (nCPAP), such …

Comparison of therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: a randomised prospective parallel trial

C Jenkinson, RJO Davies, R Mullins, JR Stradling - The Lancet, 1999 - thelancet.com
Background Nasal continuous positive airway pressure (NCPAP) is widely used as a treatment
for obstructive sleep apnoea. However, to date there are no randomised controlled trials …

Effect of home noninvasive ventilation with oxygen therapy vs oxygen therapy alone on hospital readmission or death after an acute COPD exacerbation: a …

…, N Oscroft, M Patout, J Pepperell, I Smith, JR Stradling… - Jama, 2017 - jamanetwork.com
Importance Outcomes after exacerbations of chronic obstructive pulmonary disease (COPD)
requiring acute noninvasive ventilation (NIV) are poor and there are few treatments to …

Mechanisms of vascular damage in obstructive sleep apnea

M Kohler, JR Stradling - Nature Reviews Cardiology, 2010 - nature.com
Obstructive sleep apnea (OSA) is characterized by repetitive apnea–hypopnea cycles during
sleep, which are associated with oxygen desaturation and sleep disruption. Up to 30% of …

Prevalence of obstructive sleep apnoea in men with type 2 diabetes

SD West, DJ Nicoll, JR Stradling - Thorax, 2006 - thorax.bmj.com
Background: A study was undertaken to establish the prevalence of obstructive sleep apnoea
(OSA) in men with type 2 diabetes. Methods: Men with type 2 diabetes from local hospital …

Effect of CPAP on insulin resistance and HbA1c in men with obstructive sleep apnoea and type 2 diabetes

…, DJ Nicoll, TM Wallace, DR Matthews, JR Stradling - Thorax, 2007 - thorax.bmj.com
Background: The effects of continuous positive airway pressure (CPAP) for obstructive sleep
apnoea (OSA) on insulin resistance are not clear. Trials have found conflicting results and …

A randomized controlled trial of adaptive ventilation for Cheyne–Stokes breathing in heart failure

…, N Crosthwaite, JR Stradling… - American journal of …, 2003 - atsjournals.org
Heart failure is associated with Cheyne–Stokes breathing, which fragments patients' sleep.
Correction of respiratory disturbance may reduce sleep fragmentation and excessive daytime …

Case-control study of 24 hour ambulatory blood pressure in patients with obstructive sleep apnoea and normal matched control subjects

…, RL Mullins, C Barbour, RJO Davies, JR Stradling - Thorax, 2000 - thorax.bmj.com
BACKGROUND There is considerable debate regarding the relationship between obstructive
sleep apnoea (OSA) and hypertension. It is unclear whether OSA is an independent …

Effects of continuous positive airway pressure therapy withdrawal in patients with obstructive sleep apnea: a randomized controlled trial

…, O Senn, KE Bloch, EW Russi, JR Stradling - American journal of …, 2011 - atsjournals.org
Rationale: To establish a new approach to investigate the physiological effects of obstructive
sleep apnea (OSA), and to evaluate novel treatments, during a period of continuous …

Predictors of long-term compliance with continuous positive airway pressure

M Kohler, D Smith, V Tippett, JR Stradling - Thorax, 2010 - thorax.bmj.com
Background There are very few data on objectively assessed long-term compliance with
continuous positive airway pressure (CPAP). No single factor has been consistently identified …