Rationale: Some studies have shown a beneficial effect of corticosteroids in patients with
community-acquired pneumonia (CAP), possibly by diminishing local and systemic …

Background Rational prescription of antibiotics in acute exacerbations of COPD (AECOPD)
requires predictive markers. We aimed to analyze whether markers of systemic inflammation …

Defects in motile cilia and sperm flagella cause primary ciliary dyskinesia (PCD), characterized
by chronic airway disease, infertility, and left-right laterality disturbances, usually as a …

Rationale: The role of antibiotics in acute exacerbations is controversial and their efficacy
when added to systemic corticosteroids is unknown. Objectives: We conducted a randomized, …

Defects in motile cilia and sperm flagella cause primary ciliary dyskinesia (PCD), characterized
by chronic airway disease, infertility, and left-right body axis disturbance. Here we report …

The role of antibiotics in acute exacerbations of chronic obstructive pulmonary disease (COPD)
is controversial and a biomarker identifying patients who benefit from antibiotics is …

Imagine a medicine that is expected to have very limited effects based upon knowledge of its
pharmacology and (patho)physiology and that is studied in the wrong population, with low‐…

In a clinical setting the chest radiograph is the reference standard in establishing the
diagnosis of community-acquired pneumonia (CAP). This study aimed to assess interobserver …

Hypertonic saline inhalation lowers airway mucous viscosity. Increased cough transportability
may improve quality of life (QoL) in primary ciliary dyskinesia (PCD). In this randomised …

Background Substances that potentially enhance performance (eg, recombinant human
erythropoietin [rHuEPO]) are considered doping and are therefore forbidden in sports; however, …