Background Comorbidities associated with systemic inflammation including cardiovascular
disease (CVD), stroke and diabetes mellitus (DM) are common among individuals with …

Epidemiological studies suggest that a hookworm infection producing 50 eggs/gram of feces
may protect against asthma. We conducted a dose-ranging study to identify the dose of …

Rationale: Asthma is heterogeneous and knowledge on exacerbation patterns is lacking.
Previous studies have had a relatively short follow-up or focused on severe disease. Objectives…

Rationale: Chronic hypersensitivity pneumonitis (CHP) is a condition that arises after
repeated exposure and sensitization to inhaled antigens. The lung microbiome is increasingly …

Asthma is the most common respiratory disorder in the UK, yet we have incomplete
knowledge on the prevalence of current disease, treatment and exacerbations. We used UK …

Background The assessment of small airways obstruction (SAO) using spirometry is practiced
in population-based studies. However, it is not clear what are the most used parameters …

Data from epidemiologic studies suggest that hookworm infections, in establishing an
immunologic phenotype conducive to parasite survival, may protect against the development of …

Inhalational exposures are increasingly recognized as an important component in the
development of ILDs, and novel exposure-disease associations continue to be discovered. These …

Currently the National Asthma and COPD audit programme (NACAP) only undertakes audit
of COPD primary care in Wales due to its near complete data coverage. We aimed to …

This British Thoracic Society (BTS) Clinical Statement addresses occupational asthma and
includes key clinical practice points. In an era in which medical practice is increasingly …