User profiles for Joel N. Kline
Joel N KlineProfessor of Medicine, University of Iowa Verified email at uiowa.edu Cited by 14623 |
TLR4 mutations are associated with endotoxin hyporesponsiveness in humans
There is much variability between individuals in the response to inhaled toxins, but it is not
known why certain people develop disease when challenged with environmental agents and …
known why certain people develop disease when challenged with environmental agents and …
Motile cilia of human airway epithelia are chemosensory
Cilia are microscopic projections that extend from eukaryotic cells. There are two general
types of cilia; primary cilia serve as sensory organelles, whereas motile cilia exert mechanical …
types of cilia; primary cilia serve as sensory organelles, whereas motile cilia exert mechanical …
Cutting edge: modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma
JN Kline, TJ Waldschmidt, TR Businga… - The Journal of …, 1998 - journals.aai.org
Asthma has been increasing in industrialized countries. Evidence suggests that asthma is
caused by a Th2 immune response to inhaled environmental Ags and that childhood …
caused by a Th2 immune response to inhaled environmental Ags and that childhood …
Bronchial thermoplasty: long-term safety and effectiveness in patients with severe persistent asthma
…, G Cox, DH Sterman, K Hogarth, JN Kline… - Journal of allergy and …, 2013 - Elsevier
… JN Kline has received a grant and travel support from Asthmatx and has received grants
from GSK, Teva, Boehringer Ingelheim, Pearl Therapeutics, and Genentech. AH Mansur has …
from GSK, Teva, Boehringer Ingelheim, Pearl Therapeutics, and Genentech. AH Mansur has …
Omalizumab pretreatment decreases acute reactions after rush immunotherapy for ragweed-induced seasonal allergic rhinitis
TB Casale, WW Busse, JN Kline, ZK Ballas… - Journal of Allergy and …, 2006 - Elsevier
BACKGROUND: Rush immunotherapy (RIT) presents an attractive alternative to standard
immunotherapy. However, RIT carries a much greater risk of acute allergic reactions, including …
immunotherapy. However, RIT carries a much greater risk of acute allergic reactions, including …
Health effects of airborne exposures from concentrated animal feeding operations
Toxic gases, vapors, and particles are emitted from concentrated animal feeding operations
(CAFOs) into the general environment. These include ammonia, hydrogen sulfide, carbon …
(CAFOs) into the general environment. These include ammonia, hydrogen sulfide, carbon …
Phase I/II randomized trial of aerobic exercise in Parkinson disease in a community setting
Objectives: To (1) investigate effects of aerobic walking on motor function, cognition, and quality
of life in Parkinson disease (PD), and (2) compare safety, tolerability, and fitness benefits …
of life in Parkinson disease (PD), and (2) compare safety, tolerability, and fitness benefits …
Intestinal helminths protect in a murine model of asthma
…, DE Elliott, JV Weinstock, JN Kline - The Journal of …, 2006 - journals.aai.org
Underdeveloped nations are relatively protected from the worldwide asthma epidemic; the
hygiene hypothesis suggests this is due to suppression of Th2-mediated inflammation by …
hygiene hypothesis suggests this is due to suppression of Th2-mediated inflammation by …
Variable airway responsiveness to inhaled lipopolysaccharide
JN Kline, JD Cowden, GW HUNNINGHAKE… - American journal of …, 1999 - atsjournals.org
Individuals exposed to inhaled endotoxin (lipopolysaccharide [LPS]) can develop airway
symptomatology and exacerbations of asthma. Moreover, among those occupationally exposed …
symptomatology and exacerbations of asthma. Moreover, among those occupationally exposed …
MMP9 modulates tight junction integrity and cell viability in human airway epithelia
…, S Keshavjee, P Karp, JN Kline… - … of Physiology-Lung …, 2009 - journals.physiology.org
The family of zinc- and calcium-dependent matrix metalloproteases (MMPs) play an important
role in remodeling of the airways in disease. Transcriptional regulation by proinflammatory …
role in remodeling of the airways in disease. Transcriptional regulation by proinflammatory …