Neurodegenerative disease status and post-mortem pathology in idiopathic rapid-eye-movement sleep behaviour disorder: an observational cohort study

…, D Vilas, A LLadó, C Gaig, J Santamaria - The Lancet …, 2013 - thelancet.com
Background We postulated that idiopathic rapid-eye-movement (REM) sleep behaviour disorder
(IRBD) represents the prodromal phase of a Lewy body disorder and that, with sufficient …

Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study

…, A Heidbreder, JY Montplaisir, J Santamaria… - Brain, 2019 - academic.oup.com
Idiopathic REM sleep behaviour disorder (iRBD) is a powerful early sign of Parkinson’s
disease, dementia with Lewy bodies, and multiple system atrophy. This provides an …

[HTML][HTML] Neurodegenerative disorder risk in idiopathic REM sleep behavior disorder: study in 174 patients

…, R Sánchez-Valle, A Lladó, C Gaig, J Santamaría - PloS one, 2014 - journals.plos.org
Objective To estimate the risk for developing a defined neurodegenerative syndrome in a
large cohort of idiopathic REM sleep behavior disorder (IRBD) patients with long follow-up. …

A novel non-rapid-eye movement and rapid-eye-movement parasomnia with sleep breathing disorder associated with antibodies to IgLON5: a case series …

…, C Embid, I Vilaseca, A Iranzo, J Santamaría… - The Lancet …, 2014 - thelancet.com
Background Autoimmunity might be associated with or implicated in sleep and neurodegenerative
disorders. We aimed to describe the features of a novel neurological syndrome …

Decreased striatal dopamine transporter uptake and substantia nigra hyperechogenicity as risk markers of synucleinopathy in patients with idiopathic rapid-eye …

…, B Högl, E Tolosa, W Poewe, J Santamaria - The Lancet …, 2010 - thelancet.com
Background Patients with idiopathic rapid-eye-movement sleep behaviour disorder (IRBD)
may develop neurodegenerative conditions associated with substantia nigra dysfunction …

Severe obstructive sleep apnea/hypopnea mimicking REM sleep behavior disorder

A Iranzo, J Santamaría - Sleep, 2005 - academic.oup.com
Objective: To describe the clinical and video-polysomnographic (VPSG) features of a group
of subjects with severe obstructive sleep apnea/hypopnea (OSAH) mimicking the symptoms …

The EEG of drowsiness in normal adults

J Santamaria, KH Chiappa - Journal of clinical Neurophysiology, 1987 - journals.lww.com
… Blink motions (blinks and miniblinks) were absent during DR EEG slowing in all subjects (Santamaria
and Chiappa, … One problem with these studies is that they used limited or exclusively …

Normative EMG values during REM sleep for the diagnosis of REM sleep behavior disorder

…, M Salamero, E Tolosa, W Poewe, J Santamaria… - Sleep, 2012 - academic.oup.com
Background: Correct diagnosis of rapid eye movement sleep behavior disorder (RBD) is
important because it can be the first manifestation of a neurodegenerative disease, it may lead …

Diagnosis and the premotor phase of Parkinson disease

E Tolosa, C Gaig, J Santamaría, Y Compta - Neurology, 2009 - AAN Enterprises
Clinical, neuroimaging, and pathologic studies have provided data suggesting that a variety
of nonmotor symptoms can precede the classic motor features of Parkinson disease (PD) by …

Clinical manifestations of the anti-IgLON5 disease

…, A Iranzo, G Ercilla, L Sabater, J Santamaría… - Neurology, 2017 - AAN Enterprises
Objective: To report the presentation, main syndromes, human leukocyte antigen (HLA)
association, and immunoglobulin G (IgG) subclass in the anti-IgLON5 disease: a disorder with …