[PDF][PDF] Randomized phase III trial of platinum-doublet chemotherapy followed by gefitinib compared with continued platinum-doublet chemotherapy in Japanese …
…, N Yamamoto, S Kudoh, J Sasaki… - Journal of Clinical …, 2010 - researchgate.net
Purpose Gefitinib is a small molecule inhibitor of the epidermal growth factor receptor tyrosine
kinase. We conducted a phase III trial to evaluate whether gefitinib improves survival as …
kinase. We conducted a phase III trial to evaluate whether gefitinib improves survival as …
Activity of nivolumab and utility of neutrophil-to-lymphocyte ratio as a predictive biomarker for advanced non–small-cell lung cancer: a prospective observational study
…, Y Hiyoshi, M Ishihara, M Kasajima, J Sasaki… - Clinical lung cancer, 2019 - Elsevier
Background The immune checkpoint inhibitor nivolumab is entering routine oncologic
practice. We investigated the safety and efficacy of nivolumab in the real world and alternative …
practice. We investigated the safety and efficacy of nivolumab in the real world and alternative …
[HTML][HTML] Circulating tumor cells as a prognostic factor in patients with small cell lung cancer
…, S Maki, K Katono, A Takakura, J Sasaki… - Oncology …, 2014 - spandidos-publications.com
The detection of circulating tumor cells (CTCs) in peripheral blood is currently an important
field of study. Detection of CTCs by the OBP‑401 assay (TelomeScan®) has previously been …
field of study. Detection of CTCs by the OBP‑401 assay (TelomeScan®) has previously been …
CD44 cleavage induced by a membrane-associated metalloprotease plays a critical role in tumor cell migration
I Okamoto, Y Kawano, H Tsuiki, J Sasaki, M Nakao… - Oncogene, 1999 - nature.com
CD44 is a cell surface receptor for hyaluronate, a component of the extracellular matrix (ECM).
Although CD44 has been implicated in tumor invasion and metastasis, the molecular …
Although CD44 has been implicated in tumor invasion and metastasis, the molecular …
[HTML][HTML] Prospective evaluation of the G8 screening tool for prognostication of survival in elderly patients with lung cancer: a single-institution study
Y Agemi, T Shimokawa, J Sasaki, K Miyazaki… - PLoS …, 2019 - journals.plos.org
The G8 questionnaire is a quick and easy-to-use screening tool. Several studies reported
that the G8 questionnaire had a high sensitivity for predicting abnormalities in the full …
that the G8 questionnaire had a high sensitivity for predicting abnormalities in the full …
Myristoylation of the fus1 protein is required for tumor suppression in human lung cancer cells
F Uno, J Sasaki, M Nishizaki, G Carboni, K Xu… - Cancer research, 2004 - AACR
FUS1 is a novel tumor suppressor gene identified in the human chromosome 3p21.3 region
that is deleted in many cancers. Using surface-enhanced laser desorption/ionization mass …
that is deleted in many cancers. Using surface-enhanced laser desorption/ionization mass …
Novel germline mutation: EGFR V843I in patient with multiple lung adenocarcinomas and family members with lung cancer
K Ikeda, H Nomori, T Mori, J Sasaki… - The Annals of thoracic …, 2008 - Elsevier
A novel germline transmission of the epidermal growth factor receptor (EGFR) mutation
V843I in a family with multiple members with lung cancer is reported. The proband was a 70-year…
V843I in a family with multiple members with lung cancer is reported. The proband was a 70-year…
Nitric oxide synthase activity in human lung cancer
…, H Terazaki, Y Tanaka, J Sasaki… - Japanese journal of …, 1997 - Wiley Online Library
Nitric oxide synthases (NOS) exist in human tumor cell lines and solid tumor tissues, and it
has been suggested that NO may play important roles in growth, progression or metastasis of …
has been suggested that NO may play important roles in growth, progression or metastasis of …
The role of prophylactic cranial irradiation for patients with small-cell lung cancer
Y Nakahara, J Sasaki, T Fukui, S Otani… - Japanese Journal of …, 2018 - academic.oup.com
Small-cell lung cancer (SCLC) has a particular propensity to metastasize to the brain, affecting
~10% of SCLC patients at diagnosis, but may occur in more than 50% of 2-year survivors. …
~10% of SCLC patients at diagnosis, but may occur in more than 50% of 2-year survivors. …
Mebendazole Elicits a Potent Antitumor Effect on Human Cancer Cell Lines Both in Vitro and in Vivo
We have found that mebendazole (MZ), a derivative of benzimidazole, induces a dose- and
time-dependent apoptotic response in human lung cancer cell lines. In this study, MZ …
time-dependent apoptotic response in human lung cancer cell lines. In this study, MZ …