Lung cancer is the most devastating malignancy in the world. Beyond genetic research,
epigenomic studies—especially investigations of microRNAs—have grown rapidly in quantity …

TNFα has recently emerged as a regulator linking inflammation to cancer pathogenesis, but
the detailed cellular and molecular mechanisms underlying this link remain to be elucidated. …

Background Amivantamab has been approved for the treatment of patients with advanced
non–small-cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 …

Simple Summary The prognosis of non-small cell lung cancer (NSCLC) is poor as more
than half of the patients are diagnosed at an advanced stage. The outcomes have greatly …

To identify common genetic variants that contribute to lung cancer susceptibility, we conducted
a multistage genome-wide association study of lung cancer in Asian women who never …

Genome-wide association studies of lung cancer reported in populations of European
background have identified three regions on chromosomes 5p15.33, 6p21.33, and 15q25 that …

This study is the first study to investigate the anticancer effect of 6-shogaol in human non-small
cell lung cancer A549 cells. 6-Shogaol inhibited cell proliferation by inducing autophagic …

Research on molecular mechanisms underlying the carcinogenesis of non-small cell lung
cancer (NSCLC) may provide gene targets in critical pathways valuable for improving the …

Hypoxia, the most commonly observed characteristic in cancers, is implicated in the
establishment of an immunosuppressive niche. Recent studies have indicated that extracellular …

Cancer remains a leading cause of death worldwide, despite many advances being made in
recent decades. Changes in the tumor microenvironment, including dysregulated immunity, …