Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis

…, CM Nunez, SR Patel, T Penzel, JL Pépin… - The Lancet …, 2019 - thelancet.com
Background There is a scarcity of published data on the global prevalence of obstructive
sleep apnoea, a disorder associated with major neurocognitive and cardiovascular sequelae. …

Obstructive sleep apnoea syndrome

…, RD McEvoy, VK Somers, L Lavie, JL Pépin - Nature reviews Disease …, 2015 - nature.com
Obstructive sleep apnoea syndrome (OSAS) is a common clinical condition in which the throat
narrows or collapses repeatedly during sleep, causing obstructive sleep apnoea events. …

Side effects of nasal continuous positive airway pressure in sleep apnea syndrome: study of 193 patients in two French sleep centers

JL Pépin, P Leger, D Veale, B Langevin, D Robert… - Chest, 1995 - Elsevier
… Author links open overlay panel Jean Louis Pépin MD a , Patrick Leger MD a , Dan Veale
MD c a , Bruno Langevin MD b a , Dominique Robert MD a b , Patrick Lévy MD, PhD c a …

Deficits of cognitive executive functions in patients with sleep apnea syndrome

B Naëgelé, V Thouvard, JL Pépin, P Lévy, C Bonnet… - Sleep, 1995 - academic.oup.com
Impairment of cognitive executive functions previously has been suspected to occur in
association with sleep apnea syndrome (SAS), as suggested by some neuropsychological studies…

Effective compliance during the first 3 months of continuous positive airway pressure: a European prospective study of 121 patients

JL Pepin, J Krieger, D Rodenstein… - American journal of …, 1999 - atsjournals.org
Effective compliance (time spent at the effective pressure) with nasal CPAP in obstructive
sleep apnea has been reported to be poor. The aim of our study was to evaluate effective …

Pulse transit time: an appraisal of potential clinical applications

RP Smith, J Argod, JL Pépin, PA Lévy - Thorax, 1999 - thorax.bmj.com
Current techniques for investigating patients with suspected sleep disordered breathing are
inadequate. Not only are many of the tests expensive, but they are also cumbersome and …

Improvement in quadriceps strength and dyspnea in daily tasks after 1 month of electrical stimulation in severely deconditioned and malnourished COPD

I Vivodtzev, JL Pépin, G Vottero, V Mayer, B Porsin… - Chest, 2006 - Elsevier
Study objectives Low body weight in COPD patients is associated with worsening dyspnea,
reduced leg strength, and poor prognosis. Classical rehabilitation strategies are then limited …

Mechanisms of cardiac dysfunction in obstructive sleep apnea

…, R Tamisier, P Levy, JL Pepin - Nature Reviews …, 2012 - nature.com
Obstructive sleep apnea (OSA) is associated with cardiovascular morbidity and mortality,
largely as a result of myocardial anomalies. Numerous mechanisms cause OSA-related …

Definition, discrimination, diagnosis and treatment of central breathing disturbances during sleep

…, J Montserrat, M Naughton, JL Pepin… - European respiratory …, 2017 - Eur Respiratory Soc
The complexity of central breathing disturbances during sleep has become increasingly
obvious. They present as central sleep apnoeas (CSAs) and hypopnoeas, periodic breathing …

Diabetes mellitus prevalence and control in sleep-disordered breathing: the European Sleep Apnea Cohort (ESADA) study

BD Kent, L Grote, S Ryan, JL Pepin, MR Bonsignore… - Chest, 2014 - Elsevier
BACKGROUND OSA is associated with an increased risk of cardiovascular morbidity. A
driver of this is metabolic dysfunction and in particular type 2 diabetes mellitus (T2DM). Prior …