Although declining, gastric cancer (GC) is estimated to be second in frequency worldwide.
Major causes appear to be environmental rather than genetic. A relationship has been …

Cancer is a worldwide health problem. Personalized treatment represents a future
advancement for cancer treatment, in part due to the development of targeted therapeutic drugs. …

Background Long-term changes in lung cancer (LC) patients are difficult to evaluate. We report
results from the French KBP-2020 real-life cohort. Methods KBP-2020 was a prospective …

Introduction: Bisphosphonates (BPs) are effective in preventing, reducing the incidence, and
delaying the onset of skeletal-related events in patients with bone metastases in a variety of …

Purpose: The phase II prospective, noncomparative BRAIN study (NCT00800202) investigated
efficacy and safety of bevacizumab in chemotherapy-naïve or pretreated patients with non…

The p53 alteration is the most common alteration found in human cancer. It usually involves
missense mutations that stabilize the p53 protein, which in turn accumulates, reaching levels …

Purpose: Tumor somatic mutation analysis is part of the standard management of metastatic
lung cancer. However, physicians often have to deal with small biopsies and consequently …

We identified more than 30 studies on the association between exposure to maternal tobacco
smoke during pregnancy and cancer in childhood. We combined their results in meta-…

The number of clinical protocols testing combined therapies including immune check-point
inhibitors and platinum salts is currently increasing in lung cancer treatment, however …

Lung cancer in never-smokers (LCINS) (fewer than 100 cigarettes in lifetime) is considered
as a distinct entity and harbours an original molecular profile. However, the epidemiological …