After 6 years with Xolair; a 3‐year withdrawal follow‐up

A Nopp, SGO Johansson, J Adédoyin, J Ankerst… - Allergy, 2010 - Wiley Online Library
Background: This study reports the clinical and immunological state of patients 3 years after
a 6‐year period of Xolair treatment for severe allergic asthma. Methods: The patient’s cat …

Basophil allergen threshold sensitivity: a useful approach to anti‐IgE treatment efficacy evaluation

A Nopp, SGO Johansson, J Ankerst, G Bylin… - Allergy, 2006 - Wiley Online Library
Background: Monitoring of the allergen sensitivity of a patient is most important for optimal
patient care and a basic prerequisite for immunomodulating treatment. The objective of this …

Budesonide and formoterol in a single inhaler improves asthma control compared with increasing the dose of corticosteroid in adults with mild-to-moderate asthma

UG Lalloo, J Malolepszy, D Kozma, K Krofta, J Ankerst… - Chest, 2003 - Elsevier
Background: We evaluated the efficacy and safety of low-dose budesonide/formoterol, 80 μg/4.5
μg, bid in a single inhaler (Symbicort Turbuhaler; AstraZeneca; Lund, Sweden) …

The size of the disease relevant IgE antibody fraction in relation to 'total‐IgE' predicts the efficacy of anti‐IgE (Xolair®) treatment

SGO Johansson, A Nopp, H Öman, J Ankerst… - Allergy, 2009 - Wiley Online Library
Background: Some patients with allergic asthma treated with anti‐IgE (Xolair ® ) do not
become symptom free. Better criteria for response assessment than allergy skin tests or IgE …

CD‐sens and clinical changes during withdrawal of Xolair after 6 years of treatment

A Nopp, SGO Johansson, J Ankerst, M Palmqvist… - Allergy, 2007 - Wiley Online Library
Background: Many clinical trials with omalizumab, Xolair, have been reported but the treatment
period has always been short, ie <12 months. After withdrawal, the clinical symptoms …

Circulating eosinophils in asthma, allergic rhinitis, and atopic dermatitis lack morphological signs of degranulation

M Malm‐Erjefält, L Greiff, J Ankerst… - Clinical & …, 2005 - Wiley Online Library
Background In allergic diseases, eosinophils in affected tissues release granule proteins
with cytotoxic, immunoregulatory, and remodelling‐promoting properties. From recent …

[HTML][HTML] Increase of club cell (Clara) protein (CC16) in plasma and urine after exercise challenge in asthmatics and healthy controls, and correlations to exhaled …

E Tufvesson, H Svensson, J Ankerst, L Bjermer - Respiratory medicine, 2013 - Elsevier
Exercise is known to affect the airway epithelium through dehydration, followed by a release
of mediators, such as club cell (Clara) protein (CC16). The aim of this study was to follow …

[HTML][HTML] Flow-volume parameters in COPD related to extended measurements of lung volume, diffusion, and resistance

L Jarenbäck, J Ankerst, L Bjermer, E Tufvesson - Pulmonary …, 2013 - hindawi.com
Classification of COPD into different GOLD stages is based on forced expiratory volume in 1
s (FEV 1 ) and forced vital capacity (FVC) but has shown to be of limited value. The aim of …

Hyperhomocysteinemia and changed plasma thiol redox status in chronic obstructive pulmonary disease

A Andersson, J Ankerst, A Lindgren, K Larsson… - 2001 - degruyter.com
Reduced and total homocysteine, cysteine, glutathione and cysteinylglycine in plasma were
investigated in 19 patients with chronic obstructive pulmonary disease and in 29 healthy …

Endoplasmic reticulum, Golgi, and lysosomes are disorganized in lung fibroblasts from chronic obstructive pulmonary disease patients

…, I Åberg, G Westergren‐Thorsson, J Ankerst… - Physiological …, 2018 - Wiley Online Library
Chronic Obstructive Pulmonary Disease ( COPD ) is often caused by smoking and other
stressors. This causes oxidative stress, which induces numerous changes on both the …