Arsenic trioxide has shown substantial efficacy in treating both newly diagnosed and
relapsedpatients with acute promyelocytic leukemia (APL). As a single agent, it induces complete …

Background Although laparoscopic resection of colorectal carcinoma improves post-operative
recovery, long-term survival and disease control are the determining factors for its …

Clinical acute lung injury (ALI) is a major cause of acute respiratory failure in critically ill
patients. There is considerable experimental and clinical evidence that pro- and anti-…

The American Academy of Pediatrics is committed to addressing the factors that affect child
and adolescent health with a focus on issues that may leave some children more vulnerable …

Streptococcus mutans is a bacterium that has evolved to be dependent upon a biofilm “lifestyle”
for survival and persistence in its natural ecosystem, dental plaque. We initiated this …

Hyaluronan has been implicated in biological processes such as cell adhesion, migration
and proliferation. Traditionally, it was thought to be associated with the extracellular matrix, but…

Background— Intravascular red cell hemolysis impairs nitric oxide (NO)–redox homeostasis,
producing endothelial dysfunction, platelet activation, and vasculopathy. Red blood cell …

In a previous study, a quorum-sensing signaling system essential for genetic competence in
Streptococcus mutans was identified, characterized, and found to function optimally in …

Increased production of peripheral cytokines and other pro-inflammatory markers has been
linked to psychiatric disorders such as major depressive disorder and post-traumatic stress …

Purpose: The PTEN gene at chromosome 10q23.3 is a tumor-suppressor genethat is inactivated
in several types of human tumors. Althoughmutation and homozygous deletion are the …