Cardioprotective microRNAs: Lessons from stem cell-derived exosomal microRNAs to treat cardiovascular disease

AS Moghaddam, JT Afshari, SA Esmaeili, E Saburi… - Atherosclerosis, 2019 - Elsevier
The stem cell-based therapy has emerged as a promising therapeutic strategy for treating
cardiovascular ischemic diseases (CVIDs), such as myocardial infarction (MI). However, some …

Study of cytotoxic and apoptogenic properties of saffron extract in human cancer cell lines

J Tavakkol-Afshari, A Brook, SH Mousavi - Food and Chemical Toxicology, 2008 - Elsevier
Saffron (dried stigmas of Crocus sativus L.) has been used as a spice, food colorant and
medicinal plant for millennia. In this study cytotoxic effect of saffron extract was evaluated in …

Anti‐inflammatory and immune‐modulatory impacts of berberine on activation of autoreactive T cells in autoimmune inflammation

SM Ehteshamfar, M Akhbari, JT Afshari… - Journal of cellular …, 2020 - Wiley Online Library
Autoreactive inflammatory CD4 + T cells, such as T helper (Th)1 and Th17 subtypes, have
been found to associate with the pathogenesis of autoimmune disorders. On the other hand, …

[HTML][HTML] Honey induces apoptosis in renal cell carcinoma

S Samarghandian, JT Afshari… - Pharmacognosy …, 2011 - ncbi.nlm.nih.gov
Background: The fact that antioxidants have several preventative effects against different
diseases, such as coronary diseases, inflammatory disorders, neurologic degeneration, aging, …

Role of caspases and Bax protein in saffron-induced apoptosis in MCF-7 cells

SH Mousavi, J Tavakkol-Afshari, A Brook… - Food and chemical …, 2009 - Elsevier
Saffron (Crocus sativus), widely used as a spice in Middle Eastern cuisine and is known for
anti-cancer properties. The mechanism of saffron-induced cytotoxicity, in tumor cells has not …

[HTML][HTML] Chrysin reduces proliferation and induces apoptosis in the human prostate cancer cell line pc-3

S Samarghandian, JT Afshari, S Davoodi - Clinics, 2011 - Elsevier
INTRODUCTION: Honey is a common household product with many medicinal uses described
in traditional medicine. Only recently has its antioxidant properties and preventive effects …

[HTML][HTML] Mesenchymal stromal cell therapy for COVID-19-induced ARDS patients: a successful phase 1, control-placebo group, clinical trial

…, R Ganjali, AR Tafreshian, J Tavakol-Afshari - Stem Cell Research & …, 2022 - Springer
Background Acute respiratory distress syndrome (ARDS) is the devastating complication of
the new COVID-19 pandemic, directly correlated with releasing large amounts of …

[HTML][HTML] Improving multi-epitope long peptide vaccine potency by using a strategy that enhances CD4+ T help in BALB/c mice

H Ghaffari-Nazari, J Tavakkol-Afshari, MR Jaafari… - PloS one, 2015 - journals.plos.org
Peptide-based vaccines are attractive approaches for cancer immunotherapy; but the
success of these vaccines in clinical trials have been limited. Our goal is to improve immune …

[HTML][HTML] Evaluation of serum interleukins-6, 8 and 10 levels as diagnostic markers of neonatal infection and possibility of mortality

H Boskabadi, G Maamouri, JT Afshari… - Iranian journal of …, 2013 - ncbi.nlm.nih.gov
Objective (s): Bacterial infection contributes substantially to neonatal morbidity and mortality.
Early diagnosis of neonatal sepsis is difficult because clinical signs are non-specific. We …

[HTML][HTML] Mesenchymal stem cell therapy in amyotrophic lateral sclerosis (ALS) patients: A comprehensive review of disease information and future perspectives

…, MA Khodadoust, J Tavakol-Afshari - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
Amyotrophic lateral sclerosis (ALS) is a rare deadly progressive neurological disease that
primarily affects the upper and lower motor neurons with an annual incidence rate of 0.6 to 3.8 …