Some 12 years ago, a polymorphism of the angiotensin I-converting enzyme (ACE) gene
became the first genetic element shown to impact substantially on human physical performance…

The common inheritance of approximately 20 000 genes defines each of us as human.
However, substantial variation exists between individual human genomes, including ‘replication’ …

Muscle wasting during critical illness has been suggested to contribute to survivor functional
disability (1). Two B-mode ultrasound measures have been reported that quantify wasting (2…

Objective: Functional capacity is commonly impaired after critical illness. We sought to clarify
the relationship between objective measures of physical activity, self-reported measures of …

Constrained implants are frequently used for primary total knee arthroplasty (TKA) in
patients with moderate and severe genu-valgum (> 10). This deformity presents corrective …

The relationship between bone and skeletal muscle mass may be affected by physical training.
No studies have prospectively examined the bone and skeletal muscle responses to a …

Monitors were worn on the upper arm; a demonstration of monitor use was provided to the
patient and carer or family member during the home visit, and an information sheet with the …

This chapter contains sections titled: Human Endocrine and Paracrine Renin–Angiotensin
Systems The ACE I/D Polymorphism and Human Muscle ACE and V• O2max ACE and Elite …

… Age and growth in wild fish populations are informative metrices on inter-specific demographics
as well as the impacts of environmental alterations on fish health (Johal & Rawal, 2009; …

Aims Subjects were drawn from the MUSCLE-UK Study1 being (i) invasively ventilated for>
48 hours and (ii) on ICU> 7days. At 18 months post-ICU discharge we determined:• Daily …