User profiles for Jahit Sacarlal

Jahit Sacarlal

Faculdade de Medicina, Universidade Eduardo Mondlane
Verified email at uem.mz
Cited by 8330

Efficacy of the RTS, S/AS02A vaccine against Plasmodium falciparum infection and disease in young African children: randomised controlled trial

PL Alonso, J Sacarlal, JJ Aponte, A Leach, E Macete… - The Lancet, 2004 - thelancet.com
Background Development of an effective malaria vaccine could greatly contribute to disease
control. RTS,S/AS02A is a pre-erythrocytic vaccine candidate based on Plasmodium …

Duration of protection with RTS, S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of …

PL Alonso, J Sacarlal, JJ Aponte, A Leach, E Macete… - The Lancet, 2005 - thelancet.com
Background RTS,S/AS02A is a pre-erythrocytic stage malaria vaccine that provides partial
protection against infection in malaria-naive adult volunteers and hyperimmune adults. A …

Improvement of fungal disease identification and management: combined health systems and public health approaches

…, NP Govender, A Chakrabarti, J Sacarlal… - The Lancet Infectious …, 2017 - thelancet.com
More than 1·6 million people are estimated to die of fungal diseases each year, and about a
billion people have cutaneous fungal infections. Fungal disease diagnosis requires a high …

[HTML][HTML] Genetic diversity and protective efficacy of the RTS, S/AS01 malaria vaccine

…, D Robbins, C Russ, EM Ryan, J Sacarlal… - … England Journal of …, 2015 - Mass Medical Soc
Background The RTS,S/AS01 vaccine targets the circumsporozoite protein of Plasmodium
falciparum and has partial protective efficacy against clinical and severe malaria disease in …

[HTML][HTML] Immunogenicity of the RTS, S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised …

…, A Mtoro, S Abdulla, P Aide, J Sacarlal… - The Lancet infectious …, 2015 - thelancet.com
Background The RTS,S/AS01 malaria vaccine targets the circumsporozoite protein,
inducing antibodies associated with the prevention of Plasmodium falciparum infection. We …

Safety of the RTS, S/AS02D candidate malaria vaccine in infants living in a highly endemic area of Mozambique: a double blind randomised controlled phase I/IIb trial

…, M Renom, I Mandomando, Q Bassat, J Sacarlal… - The Lancet, 2007 - thelancet.com
Background Malaria remains a leading global health problem that requires the improved
use of existing interventions and the accelerated development of new control methods. We …

Community-acquired bacteremia among children admitted to a rural hospital in Mozambique

…, L Morais, L Quintó, J Sacarlal… - The Pediatric …, 2009 - journals.lww.com
Background: Although community-acquired bacteremia is an important cause of childhood
mortality in Africa, recognition of disease burden and potential impact of bacterial vaccines is …

[PDF][PDF] Cause-specific mortality rates in sub-Saharan Africa and Bangladesh

…, H Masanja, U Adazu, J Sacarlal… - Bulletin of the World …, 2006 - SciELO Public Health
OBJECTIVE: To provide internationally comparable data on the frequencies of different causes
of death. METHODS: We analysed verbal autopsies obtained during 1999 -2002 from 12 …

[PDF][PDF] Etiology of diarrhea in children younger than 5 years of age admitted in a rural hospital of southern Mozambique

…, F Abacassamo, X Valles, J Sacarlal… - American Journal of …, 2007 - academia.edu
Diarrhea is one of the main causes of morbidity and mortality among children in sub-Saharan
Africa and one of the main causes of hospital admissions in rural areas. Stool samples …

Profile: Manhiça health research centre (Manhiça HDSS)

…, O Augusto, I Mandomando, J Sacarlal… - International journal …, 2013 - academic.oup.com
The Manhiça Health Research Centre, established in 1996 in a rural area of southern
Mozambique, currently follows around 92 000 individuals living in approximately 20 000 …