Polyunsaturated fatty acids have crucial roles in membrane biology and signaling processes
in most living organisms. However, it is only recently that molecular genetic approaches …

Lipid and carbohydrate metabolism are highly conserved processes that affect nearly all
aspects of organismal biology. Caenorhabditis elegans eat bacteria, which consist of lipids, …

Understanding the regulation of fat synthesis and the consequences of its misregulation is
of profound significance for managing the obesity epidemic and developing obesity …

Regulation of body fat storage involves signalling between centres that regulate feeding in
the brain and sites of fat storage and use in the body 1 , 2 . Here we describe an assay for …

A total of 137 microbial species, subspecies and serovars have been isolated from the bovine
mammary gland. Nucleic acid hybridization studies have restructured the classification of …

Sterol regulatory element-binding proteins (SREBPs) activate genes involved in the
synthesis and trafficking of cholesterol and other lipids and are critical for maintaining lipid …

Polyunsaturated fatty acids (PUFAs) are important membrane components and precursors
of signaling molecules. To investigate the roles of these fatty acids in growth, development, …

The sterol regulatory element binding protein (SREBP) family of transcription activators are
critical regulators of cholesterol and fatty acid homeostasis 1 , 2 . We previously …

The use of non-standard toxicity models is a hurdle in the early development of antimicrobial
peptides towards clinical applications. Herein we report an extensive in vitro and in vivo …

The sterol regulatory element-binding protein (SREBP) transcription factor family is a critical
regulator of lipid and sterol homeostasis in eukaryotes. In mammals, SREBPs are highly …