Sinonasal carcinoma: clinical, pathological, genetic and therapeutic advances

JL Llorente, F López, C Suárez… - Nature Reviews Clinical …, 2014 - nature.com
The sinonasal cavities represent an anatomical region affected by a variety of tumours with
clinical, aetiological, pathological, and genetic features distinct from tumours at the main …

Jugular and vagal paragangliomas: systematic study of management with surgery and radiotherapy

C Suárez, JP Rodrigo, CC Bödeker, JL Llorente… - Head & …, 2013 - Wiley Online Library
Background The definitive treatment for head and neck paraganglioma (PG) is surgical excision.
Unfortunately, surgery, particularly of vagal paraganglioma (VPG; “glomus vagale”) and …

Management of the orbit in malignant sinonasal tumors

…, JJ Fagan, JP Rodrigo, JL Llorente… - Head & Neck …, 2008 - Wiley Online Library
Malignant ethmoid and maxillary sinus tumors frequently involve the orbit. Orbital involvement
is an important prognostic predictor of recurrence‐free, disease‐specific, and overall …

Predisposing factors to bacterial colonization in chronic obstructive pulmonary disease

…, V Achotegui, JI Pijoan, JL Llorente - European …, 1999 - Eur Respiratory Soc
The aim of this prospective observational study was to determine those factors influencing
bacterial colonization in patients with stable chronic obstructive pulmonary disease (COPD). …

Prognostic factors in sinonasal tumors involving the anterior skull base

C Suarez, JL Llorente… - Head & Neck …, 2004 - Wiley Online Library
Background. Anterior craniofacial resection is a standardized procedure for the treatment of
ethmoid and frontal orbital tumors with intracranial invasion. Methods. A retrospective review …

Squamous cell carcinoma of the external auditory canal

D Lobo, JL Llorente, C Suárez - Skull Base, 2008 - thieme-connect.com
Objectives: This study aims to analyze the treatments, prognostic variables, and outcomes
of patients with squamous cell carcinomas (SCC) of the external auditory canal (EAC) and …

[HTML][HTML] Comprehensive genomic diagnosis of non-syndromic and syndromic hereditary hearing loss in Spanish patients

…, N García-González, I Hernando, JL Llorente… - BMC Medical …, 2018 - Springer
Background Sensorineural hearing loss (SNHL) is the most common sensory impairment.
Comprehensive next-generation sequencing (NGS) has become the standard for the …

[HTML][HTML] Cell–cell adhesion genes CTNNA2 and CTNNA3 are tumour suppressors frequently mutated in laryngeal carcinomas

…, T Fontanil, Á Obaya, AJ Ramsay, JL Llorente… - Nature …, 2013 - nature.com
Laryngeal squamous cell carcinoma is a frequent and significant cause of morbidity and
mortality. Here we explore the biological basis of this aggressive tumour, and identify two cell–…

Paranasal sinuses mucoceles. Our experience in 72 patients

S Obeso, JL Llorente, JP Rodrigo, R Sánchez… - Acta …, 2009 - Elsevier
Introduction Traditional treatment for paranasal sinuses mucoceles recommended total
removal through external approaches. Since the 90s, endoscopic marsupialization has been …

IDH2 mutation analysis in undifferentiated and poorly differentiated sinonasal carcinomas for diagnosis and clinical management

…, V Blanco, F López, A Franchi, JL Llorente… - The American Journal …, 2020 - journals.lww.com
A large number of tumor types arise from the mucosa of the sinonasal cavities. Although
presenting clinically distinct behavior, due to poorly differentiated histologic features, they can …