Effect of ramipril vs amlodipine on renal outcomes in hypertensive nephrosclerosis: a randomized controlled trial

…, DA Cheek, W Cleveland, JG Douglas, M Douglas… - Jama, 2001 - jamanetwork.com
ContextIncidence of end-stage renal disease due to hypertension has increased in recent
decades, but the optimal strategy for treatment of hypertension to prevent renal failure is …

Nitric oxide mediates mitogenic effect of VEGF on coronary venular endothelium

L Morbidelli, CHO Chang, JG Douglas… - American Journal …, 1996 - journals.physiology.org
Vascular endothelial growth factor (VEGF) is a secreted protein that is a specific growth
factor for endothelial cells. We have recently demonstrated that nitric oxide (NO) donors and …

The treatment of brain metastases from malignant melanoma

JG Douglas, K Margolin - Seminars in oncology, 2002 - Elsevier
Metastasis to the CNS develops in nearly half of patients with advanced melanoma; in 15%
to 20% of these patients, the CNS is the first site of relapse. While systemic therapy for …

Management of high blood pressure in African Americans: consensus statement of the Hypertension in African Americans Working Group of the International Society …

JG Douglas, GL Bakris, M Epstein… - Archives of internal …, 2003 - jamanetwork.com
The purpose of this consensus statement is to offer primary care providers (including physicians,
nurse practitioners, and physician assistants) a practical, evidence-based clinical tool …

Quality of life and hospital re-admission in patients with chronic obstructive pulmonary disease.

…, DJ Godden, JA Friend, JS Legge, JG Douglas - Thorax, 1997 - thorax.bmj.com
BACKGROUND: There is some evidence that quality of life (QOL) in patients with chronic
obstructive pulmonary disease (COPD) may predict clinical outcomes and use of resources. …

[HTML][HTML] Nitric oxide is an upstream signal of vascular endothelial growth factor-induced extracellular signal-regulated kinase˝ activation in postcapillary endothelium

A Parenti, L Morbidelli, XL Cui, JG Douglas… - Journal of Biological …, 1998 - ASBMB
We recently demonstrated that nitric oxide (NO) significantly contributes to the mitogenic effect
of vascular endothelial growth factor (VEGF), suggesting a role for the NO pathway in the …

Pharmacokinetic factors in the modern drug treatment of tuberculosis

JG Douglas, MJ McLeod - Clinical pharmacokinetics, 1999 - Springer
Tuberculosis is increasing in prevalence throughout the world, particularly in sub-Saharan
Africa, Asia and Latin America. This resurgence can partly be attributed to increasing poverty, …

Angiotensin receptor subtypes of the kidney cortex

JG Douglas - American Journal of Physiology-Renal …, 1987 - journals.physiology.org
Angiotensin II (ANG II) binds with high affinity to specific renal receptors and exerts major
influences on hemodynamics and tubular transport. Glomerular and tubular epithelial receptors …

Nasal epithelial cells as surrogates for bronchial epithelial cells in airway inflammation studies

CM McDougall, MG Blaylock, JG Douglas… - American journal of …, 2008 - atsjournals.org
The nose is an attractive source of airway epithelial cells, particularly in populations in
which bronchoscopy may not be possible. However, substituting nasal cells for bronchial …

Treatment of locally advanced adenoid cystic carcinoma of the head and neck with neutron radiotherapy

JG Douglas, GE Laramore, M Austin-Seymour… - International Journal of …, 2000 - Elsevier
Purpose: To examine the efficacy of fast neutron radiotherapy for the treatment of locally
advanced and/or recurrent adenoid cystic carcinoma of the head and neck and to identify …