User profiles for JG Aerts

Joachim Aerts

Verified email at erasmusmc.nl
Cited by 29987

Novel insights into mesothelioma biology and implications for therapy

TA Yap, JG Aerts, S Popat, DA Fennell - Nature Reviews Cancer, 2017 - nature.com
Malignant mesothelioma is a universally lethal cancer that is increasing in incidence
worldwide. There is a dearth of effective therapies, with only one treatment (pemetrexed and …

Tumor-specific cytotoxic T cells are crucial for efficacy of immunomodulatory antibodies in patients with lung cancer

JG Aerts, JP Hegmans - Cancer research, 2013 - AACR
Aerts has received honoraria for service on the speakers' bureau and is a consultant/advisory
board member of Roche. No potential conflicts of interest were disclosed by the other …

[HTML][HTML] Nivolumab versus docetaxel in advanced squamous-cell non–small-cell lung cancer

…, M Steins, MC Garassino, JG Aerts… - … England Journal of …, 2015 - Mass Medical Soc
Background Patients with advanced squamous-cell non–small-cell lung cancer (NSCLC)
who have disease progression during or after first-line chemotherapy have limited treatment …

[HTML][HTML] Treatment guidance for patients with lung cancer during the coronavirus 2019 pandemic

…, GW Warren, SY Xiao, EF Smit, JG Aerts… - Journal of Thoracic …, 2020 - Elsevier
The global coronavirus disease 2019 pandemic continues to escalate at a rapid pace inundating
medical facilities and creating substantial challenges globally. The risk of severe acute …

Estimated global proportions of individuals with persistent fatigue, cognitive, and respiratory symptom clusters following symptomatic COVID-19 in 2020 and 2021

SW Hanson, C Abbafati, JG Aerts, Z Al-Aly… - Jama, 2022 - jamanetwork.com
Importance Some individuals experience persistent symptoms after initial symptomatic
SARS-CoV-2 infection (often referred to as Long COVID). Objective To estimate the proportion of …

[PDF][PDF] The PD-1/PD-L1-checkpoint restrains T cell immunity in tumor-draining lymph nodes

…, DJ Grünhagen, C Verhoef, T van Hall, JG Aerts - Cancer cell, 2020 - cell.com
PD-1/PD-L1-checkpoint blockade therapy is generally thought to relieve tumor cell-mediated
suppression in the tumor microenvironment but PD-L1 is also expressed on non-tumor …

[HTML][HTML] IMpower150 final exploratory analyses for atezolizumab plus bevacizumab and chemotherapy in key NSCLC patient subgroups with EGFR mutations or …

…, F Cappuzzo, TSK Mok, G Finley, JG Aerts… - Journal of Thoracic …, 2022 - Elsevier
Introduction Final overall survival (OS) analyses are presented for EGFR mutations and liver
or brain metastases subgroups in the phase 3 IMpower150 study (NCT02366143) …

Characteristics of lung cancers detected by computer tomography screening in the randomized NELSON trial

…, HJM Groen, JWJ Lammers, JG Aerts… - American journal of …, 2013 - atsjournals.org
Rationale: The NELSON (Nederlands Leuvens Longkanker Screenings Onderzoek) trial is,
with 15,822 participants, the largest European lung cancer computer tomography screening …

[HTML][HTML] Maintenance bevacizumab–pemetrexed after first-line cisplatin–pemetrexed–bevacizumab for advanced nonsquamous nonsmall-cell lung cancer: updated …

…, MJ Ahn, M Reck, A Pazzola, HT Kim, JG Aerts… - Annals of oncology, 2014 - Elsevier
Background The randomized, phase III AVAPERL trial evaluated the safety and efficacy of
bevacizumab maintenance with or without pemetrexed in nonsquamous nonsmall-cell lung …

Consolidative dendritic cell-based immunotherapy elicits cytotoxicity against malignant mesothelioma

…, HC Hoogsteden, BN Lambrecht, JG Aerts - American journal of …, 2010 - atsjournals.org
Rationale: We previously demonstrated that dendritic cell-based immunotherapy induced
protective antitumor immunity with a prolonged survival rate in mice. However, the clinical …