User profiles for JG Aerts
Joachim AertsVerified email at erasmusmc.nl Cited by 29987 |
Novel insights into mesothelioma biology and implications for therapy
Malignant mesothelioma is a universally lethal cancer that is increasing in incidence
worldwide. There is a dearth of effective therapies, with only one treatment (pemetrexed and …
worldwide. There is a dearth of effective therapies, with only one treatment (pemetrexed and …
Tumor-specific cytotoxic T cells are crucial for efficacy of immunomodulatory antibodies in patients with lung cancer
JG Aerts, JP Hegmans - Cancer research, 2013 - AACR
… Aerts has received honoraria for service on the speakers' bureau and is a consultant/advisory
board member of Roche. No potential conflicts of interest were disclosed by the other …
board member of Roche. No potential conflicts of interest were disclosed by the other …
[HTML][HTML] Nivolumab versus docetaxel in advanced squamous-cell non–small-cell lung cancer
…, M Steins, MC Garassino, JG Aerts… - … England Journal of …, 2015 - Mass Medical Soc
Background Patients with advanced squamous-cell non–small-cell lung cancer (NSCLC)
who have disease progression during or after first-line chemotherapy have limited treatment …
who have disease progression during or after first-line chemotherapy have limited treatment …
[HTML][HTML] Treatment guidance for patients with lung cancer during the coronavirus 2019 pandemic
The global coronavirus disease 2019 pandemic continues to escalate at a rapid pace inundating
medical facilities and creating substantial challenges globally. The risk of severe acute …
medical facilities and creating substantial challenges globally. The risk of severe acute …
Estimated global proportions of individuals with persistent fatigue, cognitive, and respiratory symptom clusters following symptomatic COVID-19 in 2020 and 2021
Importance Some individuals experience persistent symptoms after initial symptomatic
SARS-CoV-2 infection (often referred to as Long COVID). Objective To estimate the proportion of …
SARS-CoV-2 infection (often referred to as Long COVID). Objective To estimate the proportion of …
[PDF][PDF] The PD-1/PD-L1-checkpoint restrains T cell immunity in tumor-draining lymph nodes
PD-1/PD-L1-checkpoint blockade therapy is generally thought to relieve tumor cell-mediated
suppression in the tumor microenvironment but PD-L1 is also expressed on non-tumor …
suppression in the tumor microenvironment but PD-L1 is also expressed on non-tumor …
[HTML][HTML] IMpower150 final exploratory analyses for atezolizumab plus bevacizumab and chemotherapy in key NSCLC patient subgroups with EGFR mutations or …
Introduction Final overall survival (OS) analyses are presented for EGFR mutations and liver
or brain metastases subgroups in the phase 3 IMpower150 study (NCT02366143) …
or brain metastases subgroups in the phase 3 IMpower150 study (NCT02366143) …
Characteristics of lung cancers detected by computer tomography screening in the randomized NELSON trial
…, HJM Groen, JWJ Lammers, JG Aerts… - American journal of …, 2013 - atsjournals.org
Rationale: The NELSON (Nederlands Leuvens Longkanker Screenings Onderzoek) trial is,
with 15,822 participants, the largest European lung cancer computer tomography screening …
with 15,822 participants, the largest European lung cancer computer tomography screening …
[HTML][HTML] Maintenance bevacizumab–pemetrexed after first-line cisplatin–pemetrexed–bevacizumab for advanced nonsquamous nonsmall-cell lung cancer: updated …
…, MJ Ahn, M Reck, A Pazzola, HT Kim, JG Aerts… - Annals of oncology, 2014 - Elsevier
Background The randomized, phase III AVAPERL trial evaluated the safety and efficacy of
bevacizumab maintenance with or without pemetrexed in nonsquamous nonsmall-cell lung …
bevacizumab maintenance with or without pemetrexed in nonsquamous nonsmall-cell lung …
Consolidative dendritic cell-based immunotherapy elicits cytotoxicity against malignant mesothelioma
…, HC Hoogsteden, BN Lambrecht, JG Aerts - American journal of …, 2010 - atsjournals.org
Rationale: We previously demonstrated that dendritic cell-based immunotherapy induced
protective antitumor immunity with a prolonged survival rate in mice. However, the clinical …
protective antitumor immunity with a prolonged survival rate in mice. However, the clinical …