During an infection, neutrophils are the first immune cells to arrive armed to clear the invading
pathogen. In order to do so, neutrophils need to transmigrate from the peripheral blood …

During systemic inflammation different neutrophil subsets are mobilized to the peripheral
blood. These neutrophil subsets can be distinguished from normal circulating neutrophils (…

… Liñares & JD Langereis, unpublished results). Additionally, deletion of the licA gene from
the genome of a selection of these clinical NTHi isolates, which decreased or abrogated …

… van der Maten E, de Jonge MI, de Groot R, van der Flier M, Langereis JD. A versatile assay
to determine bacterial and host factors contributing to opsonophagocytotic killing in hirudin-…

The incidence of severe Haemophilus influenza infections, such as sepsis and meningitis,
has declined substantially since the introduction of the H. influenzae serotype b vaccine. …

Long-lasting and sterile homologous protection against malaria can be achieved by the
exposure of malaria-naive volunteers under chemoprophylaxis to Plasmodium falciparum -…

The immune inhibitory checkpoint molecule programmed death ligand (PD-L)-1 is increasingly
recognized as an important player in the immune suppression observed in patients with …

Background Neutrophil accumulation in the skin is a hallmark of psoriasis. Novel insights on
neutrophil phenotypic and functional heterogeneity raise the question to what extent these …

Background Bacterial respiratory tract infections, mainly caused by Streptococcus pneumoniae,
Haemophilus influenzae and Moraxella catarrhalis are among the leading causes of …

Non‐typeable H aemophilus influenzae is an opportunistic pathogen of the human upper
respiratory tract and is often found to cause inflammatory diseases that include sinusitis, otitis …