Social cognition in attention-deficit hyperactivity disorder (ADHD)

…, J Hebebrand, I Daum, J Wiltfang… - … & biobehavioral reviews, 2010 - Elsevier
Attention-deficit hyperactivity disorder (ADHD) is associated with a range of cognitive
deficits and social cognition impairments, which might be interpreted in the context of fronto-striatal …

Therapeutic approaches to Alzheimer's disease

HW Klafki, M Staufenbiel, J Kornhuber, J Wiltfang - Brain, 2006 - academic.oup.com
Alzheimer's disease is an age-related progressive neurodegenerative disorder with an
enormous unmet medical need. It is the most common form of dementia affecting ∼5% of adults …

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the …

…, M Otto, B Mollenhauer, J Wiltfang… - The world journal of …, 2018 - Taylor & Francis
In the 12 years since the publication of the first Consensus Paper of the WFSBP on biomarkers
of neurodegenerative dementias, enormous advancement has taken place in the field, …

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

…, I Heuser, J Kornhuber, J Wiltfang… - Nature …, 2009 - nature.com
We undertook a two-stage genome-wide association study (GWAS) of Alzheimer's disease (AD)
involving over 16,000 individuals, the most powerful AD GWAS to date. In stage 1 (3,941 …

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

…, I Heuser, J Kornhuber, J Wiltfang… - Nature …, 2011 - nature.com
We sought to identify new susceptibility loci for Alzheimer's disease through a staged
association study (GERAD+) and by testing suggestive loci reported by the Alzheimer's Disease …

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis

…, G Waldemar, A Wallin, ĹK Wallin, J Wiltfang… - Jama, 2015 - jamanetwork.com
Importance Cerebral amyloid-β aggregation is an early pathological event in Alzheimer
disease (AD), starting decades before dementia onset. Estimates of the prevalence of amyloid …

Growth and transplantation of a custom vascularised bone graft in a man

PH Warnke, ING Springer, J Wiltfang, Y Acil, H Eufinger… - The Lancet, 2004 - thelancet.com
Background A major goal of research in bone transplantation is the ability to avoid creation
of secondary bone defects. We aimed to repair an extended mandibular discontinuity defect …

Improved discrimination of AD patients using β-amyloid(1-42) and tau levels in CSF

…, PP Deyn, C Bancher, P Cras, J Wiltfang… - Neurology, 1999 - AAN Enterprises
Objective: To evaluate CSF levels of β-amyloid (1-42) (Aβ 42 ) alone and in combination with
CSF tau for distinguishing AD from other conditions. Methods: At 10 centers in Europe and …

Presenilin clinical mutations can affect γ‐secretase activity by different mechanisms

…, A Tolia, K Horré, J Wiltfang… - Journal of …, 2006 - Wiley Online Library
Mutations in human presenilin (PS) genes cause aggressive forms of familial Alzheimer's
disease. Presenilins are polytopic proteins that harbour the catalytic site of the γ‐secretase …

The mechanism of γ‐secretase dysfunction in familial Alzheimer disease

…, H Esselmann, J Wiltfang… - The EMBO …, 2012 - embopress.org
… and 0.075 M instead of 0.1 MH2so4 in the separation gel) (Wiltfang et al, 2002). Western
immunoblot was done using 1E8, amplifying the signal with biotinylated anti-mouse IgG and …