Acute exposure to diesel exhaust increases IL-8 and GRO-α production in healthy human airways

…, A Blomberg, B Rudell, J Pourazar… - American journal of …, 2000 - atsjournals.org
We have previously demonstrated that short-term exposure to diesel exhaust (DE) for 1 h
induced a marked leukocytic infiltration in the airways of healthy human volunteers involving …

Diesel exhaust inhalation increases thrombus formation in man

…, D Faratian, SL Barath, J Pourazar… - European heart …, 2008 - academic.oup.com
Aims Although the mechanism is unclear, exposure to traffic-derived air pollution is a trigger
for acute myocardial infarction (MI). The aim of this study is to investigate the effect of diesel …

Particle traps prevent adverse vascular and prothrombotic effects of diesel engine exhaust inhalation in men

…, MK Sidhu, JP Langrish, NA Boon, J Pourazar… - Circulation, 2011 - Am Heart Assoc
Background— In controlled human exposure studies, diesel engine exhaust inhalation impairs
vascular function and enhances thrombus formation. The aim of the present study was to …

Diesel exhaust enhances airway responsiveness in asthmatic subjects

C Nordenhäll, J Pourazar, MC Ledin… - European respiratory …, 2001 - Eur Respiratory Soc
Particulate matter (PM) pollution has been associated with negative health effects, including
exacerbations of asthma following exposure to PM peaks. The aim of the present study was …

Diesel exhaust activates redox-sensitive transcription factors and kinases in human airways

J Pourazar, IS Mudway, JM Samet… - … of Physiology-Lung …, 2005 - journals.physiology.org
Diesel exhaust (DE) is a major component of airborne particulate matter. In previous studies
we have described the acute inflammatory response of the human airway to inhaled DE. …

Airway inflammation following exposure to diesel exhaust: a study of time kinetics using induced sputum

C Nordenhall, J Pourazar, A Blomberg… - European …, 2000 - Eur Respiratory Soc
Nordenhall 1046..1051 Page 1 Airway inflammation following exposure to diesel exhaust: a
study of time kinetics using induced sputum C. NordenhaÈll*, J. Pourazar*, A. Blomberg*, JO…

[HTML][HTML] Antioxidant airway responses following experimental exposure to wood smoke in man

…, J Bosson, S Barath, AF Behndig, J Pourazar… - Particle and fibre …, 2010 - Springer
Background Biomass combustion contributes to the production of ambient particulate matter
(PM) in rural environments as well as urban settings, but relatively little is known about the …

Altered nitric oxide bioavailability contributes to diesel exhaust inhalation‐induced cardiovascular dysfunction in man

…, S Blackwell, S Söderberg, J Pourazar… - Journal of the …, 2013 - Am Heart Assoc
Background Diesel exhaust inhalation causes cardiovascular dysfunction including impaired
vascular reactivity, increased blood pressure, and arterial stiffness. We investigated the …

Dendritic cells and monocytes with distinct inflammatory responses reside in lung mucosa of healthy humans

…, G Rankin, R Lepzien, J Pourazar… - The Journal of …, 2016 - journals.aai.org
Every breath we take contains potentially harmful pathogens or allergens. Dendritic cells (DCs),
monocytes, and macrophages are essential in maintaining a delicate balance of …

[HTML][HTML] Acute exposure to wood smoke from incomplete combustion-indications of cytotoxicity

…, J Unosson, JA Bosson, A Behndig, J Pourazar… - Particle and fibre …, 2015 - Springer
Background Smoke from combustion of biomass fuels is a major risk factor for respiratory
disease, but the underlying mechanisms are poorly understood. The aim of this study was to …