Emphysema is mainly caused by cigarette smoking and is characterized by the loss of alveolar
integrity and an enlargement of the alveolar space. However, mechanisms involved in its …

Background: Severe pulmonary injury with thedevelopment of ARDS is a potential
complication of cardiac surgery and cardiopulmonary bypass (CPB). Study objectives: …

… A new method for the detection and recording of the aeulocardiae reflex (OCR J is described
and applied to 49 healthy infants and children (six months to nine years old) undergoing …

Background Current asthma guidelines suggest a series of criteria to assess if asthma is
controlled. However, there is a need to develop a simple and practical method to quantify the …

The International Pseudomonas aeruginosa Consortium is sequencing over 1000 genomes
and building an analysis pipeline for the study of Pseudomonas genome evolution, …

Background Omalizumab is an established anti-IgE therapy for the treatment of allergic
diseases that prevents IgE from binding to its receptor. QGE031 is an investigational anti-IgE …

Background Phosphodiesterase 4 (PDE4) inhibitors increase intracellular cyclic adenosine
monophosphate (cAMP), leading to regulation of inflammatory cell functions. Roflumilast is a …

The physiopathology of chronic cough remains obscure. We evaluated the possibility that
chronic cough in nonasthmatic subjects is associated with airway inflammation, and if this is so…

Background: The responsiveness of the endurance shuttle walk to functional changes
following bronchodilation has recently been reported. The current literature suggests that the 6 …

We previously reported that diisocyanate-human serum albumin (DIISO-HSA) stimulated
production of monocyte chemoattractant protein-1 (MCP-1) by peripheral blood mononuclear …