User profiles for J. Lötvall

Lotvall

Professor of Allergy, University of Gothenburg
Verified email at gu.se
Cited by 67545

Biological properties of extracellular vesicles and their physiological functions

…, A Linē, G Lipps, A Llorente, J Lötvall… - Journal of …, 2015 - Taylor & Francis
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …

Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome

J Lötvall, CA Akdis, LB Bacharier, L Bjermer… - Journal of Allergy and …, 2011 - Elsevier
It is increasingly clear that asthma is a complex disease made up of number of disease
variants with different underlying pathophysiologies. Limited knowledge of the mechanisms of …

Advances in therapeutic applications of extracellular vesicles

OPB Wiklander, MÁ Brennan, J Lötvall… - Science translational …, 2019 - science.org
Extracellular vesicles (EVs) are nanometer-sized, lipid membrane–enclosed vesicles secreted
by most, if not all, cells and contain lipids, proteins, and various nucleic acid species of …

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

…, A Bossios, M Sjöstrand, JJ Lee, JO Lötvall - Nature cell …, 2007 - nature.com
Exosomes are vesicles of endocytic origin released by many cells. These vesicles can mediate
communication between cells, facilitating processes such as antigen presentation. Here, …

Standardization of sample collection, isolation and analysis methods in extracellular vesicle research

…, LT Bemis, A Bora, C Lässer, J Lötvall… - Journal of …, 2013 - Taylor & Francis
The emergence of publications on extracellular RNA (exRNA) and extracellular vesicles (EV)
has highlighted the potential of these molecules and vehicles as biomarkers of disease …

Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular …

J Lötvall, AF Hill, F Hochberg, EI Buzás… - Journal of …, 2014 - Wiley Online Library
… in this editorial therefore will increase awareness of all researchers for potential confounders
in their EV-related results, and thus help editors and reviewers of journals other than J

[HTML][HTML] Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation

…, EM Krämer-Albers, SK Lim, A Llorente, J Lötvall… - PLoS …, 2012 - journals.plos.org
Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into
their microenvironment. Recent studies have elucidated the role of EVs in intercellular …

Applying extracellular vesicles based therapeutics in clinical trials–an ISEV position paper

…, MJ Lorenowicz, SK Lim, J Lötvall… - Journal of …, 2015 - Taylor & Francis
Extracellular vesicles (EVs), such as exosomes and microvesicles, are released by different
cell types and participate in physiological and pathophysiological processes. EVs mediate …

International consensus on (ICON) pediatric asthma

…, AH Liu, RF Lockey, K Lødrup‐Carlsen, J Lötvall… - Allergy, 2012 - Wiley Online Library
Asthma is the most common chronic lower respiratory disease in childhood throughout the
world. Several guidelines and/or consensus documents are available to support medical …

Efficacy and safety of a recombinant anti‐immunoglobulin E antibody (omalizumab) in severe allergic asthma

…, AG Chuchalin, J Hebert, J Lötvall… - Clinical & …, 2004 - Wiley Online Library
Background Patients with severe asthma are often inadequately controlled on existing anti‐asthma
therapy, constituting an unmet clinical need. Objective This randomized, double‐blind…