User profiles for J. Lötvall
LotvallProfessor of Allergy, University of Gothenburg Verified email at gu.se Cited by 67545 |
Biological properties of extracellular vesicles and their physiological functions
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …
Asthma endotypes: a new approach to classification of disease entities within the asthma syndrome
It is increasingly clear that asthma is a complex disease made up of number of disease
variants with different underlying pathophysiologies. Limited knowledge of the mechanisms of …
variants with different underlying pathophysiologies. Limited knowledge of the mechanisms of …
Advances in therapeutic applications of extracellular vesicles
Extracellular vesicles (EVs) are nanometer-sized, lipid membrane–enclosed vesicles secreted
by most, if not all, cells and contain lipids, proteins, and various nucleic acid species of …
by most, if not all, cells and contain lipids, proteins, and various nucleic acid species of …
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
…, A Bossios, M Sjöstrand, JJ Lee, JO Lötvall - Nature cell …, 2007 - nature.com
Exosomes are vesicles of endocytic origin released by many cells. These vesicles can mediate
communication between cells, facilitating processes such as antigen presentation. Here, …
communication between cells, facilitating processes such as antigen presentation. Here, …
Standardization of sample collection, isolation and analysis methods in extracellular vesicle research
The emergence of publications on extracellular RNA (exRNA) and extracellular vesicles (EV)
has highlighted the potential of these molecules and vehicles as biomarkers of disease …
has highlighted the potential of these molecules and vehicles as biomarkers of disease …
Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular …
… in this editorial therefore will increase awareness of all researchers for potential confounders
in their EV-related results, and thus help editors and reviewers of journals other than J …
in their EV-related results, and thus help editors and reviewers of journals other than J …
[HTML][HTML] Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation
…, EM Krämer-Albers, SK Lim, A Llorente, J Lötvall… - PLoS …, 2012 - journals.plos.org
Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into
their microenvironment. Recent studies have elucidated the role of EVs in intercellular …
their microenvironment. Recent studies have elucidated the role of EVs in intercellular …
Applying extracellular vesicles based therapeutics in clinical trials–an ISEV position paper
…, MJ Lorenowicz, SK Lim, J Lötvall… - Journal of …, 2015 - Taylor & Francis
Extracellular vesicles (EVs), such as exosomes and microvesicles, are released by different
cell types and participate in physiological and pathophysiological processes. EVs mediate …
cell types and participate in physiological and pathophysiological processes. EVs mediate …
International consensus on (ICON) pediatric asthma
…, AH Liu, RF Lockey, K Lødrup‐Carlsen, J Lötvall… - Allergy, 2012 - Wiley Online Library
Asthma is the most common chronic lower respiratory disease in childhood throughout the
world. Several guidelines and/or consensus documents are available to support medical …
world. Several guidelines and/or consensus documents are available to support medical …
Efficacy and safety of a recombinant anti‐immunoglobulin E antibody (omalizumab) in severe allergic asthma
…, AG Chuchalin, J Hebert, J Lötvall… - Clinical & …, 2004 - Wiley Online Library
Background Patients with severe asthma are often inadequately controlled on existing anti‐asthma
therapy, constituting an unmet clinical need. Objective This randomized, double‐blind…
therapy, constituting an unmet clinical need. Objective This randomized, double‐blind…