Exacerbated inflammation is now recognized as an important component of cystic fibrosis (CF)
airway disease. Whether inflammation is part of the basic defect in CF or a response to …

Embryonic stem (ES) cells are self-renewable and pluripotent cells derived from the inner cell
mass of a blastocyst-stage embryo. ES cell pluripotency is being investigated increasingly …

Accumulating evidence suggests that the early pulmonary inflammation pathogenesis in
cystic fibrosis (CF) may be associated with an abnormal increase in the production of pro-…

… (J) nidogen, which is also detected in the cells under the BM. Nuclei are stained blue in (C)
and (D). The scale bar represents 5.5 m in (J) … J. been deleted by homologous recombination …

The cell migration that occurs during wound repair is dependent on modifications of the cell-matrix
interaction in which extracellular matrix proteins and their receptors, the integrins, are …

Cystic fibrosis (CF) is caused by mutations in the gene coding for the CF transmembrane
conductance regulator (CFTR). From human normal tracheal submucosal gland cells in culture, …

To investigate the role of P. aeruginosa virulence factors in the repair of human airway
epithelial cells (HAEC) in culture, we evaluated the effect of stationary-phase supernatants from …

Materials and Methods Generation of Anti-CFTR Antibodies A monoclonal antibody, MATG
1061, was raised against a synthetic peptide corresponding to CFTR amino acid position 503 …

In cystic fibrosis (CF), whether cystic fibrosis transmembrane conductance regulator (CFTR)
dysfunction leads to decreased mucociliary clearance and mucus hypersecretion, before …

Human surface respiratory epithelial (HSRE) cells from nasal polyps have been cultured
within collagen lattices in a serum-free defined medium. Cell growth observed over a period of …