Background Mechanical ventilation is common in critically ill patients. This life-saving
treatment can cause complications and is also associated with long-term sequelae. Patient-…

Viscoelastic fluids are a common subclass of rheologically complex materials that are
encountered in diverse fields from biology to polymer processing. Often the flows of viscoelastic …

Organ crosstalk is an emerging area of research in lung disease in critically ill patients. The
findings of these studies are clinically relevant and show the importance of an integrative …

Brain and/or lung injury is the most frequent cause of admission to critical care units and
patients in this setting frequently develop multiple organ dysfunction with high rates of morbidity …

Purpose This study aimed to assess the prevalence and time course of asynchronies during
mechanical ventilation (MV). Methods Prospective, noninterventional observational study of …

Introduction Survivors of critical illness often have significant long-term brain dysfunction,
and routine clinical procedures like mechanical ventilation (MV) may affect long-term brain …

Objectives: Double cycling generates larger than expected tidal volumes that contribute to
lung injury. We analyzed the incidence, mechanisms, and physiologic implications of double …

Oxygen therapy is currently used as a supportive treatment in septic patients to improve tissue
oxygenation. However, oxygen can exert deleterious effects on the inflammatory response …

Background In critically ill patients, poor patient-ventilator interaction may worsen outcomes.
Although sedatives are often administered to improve comfort and facilitate ventilation, they …

Background Intensive Care Unit (ICU) COVID-19 survivors may present long-term cognitive
and emotional difficulties after hospital discharge. This study aims to characterize the …