User profiles for Ivan Gudelj

Ivan Gudelj

Assistant Professor at Faculty of Biotechnology and Drug Development, University of Rijeka
Verified email at uniri.hr
Cited by 1977

[HTML][HTML] Immunoglobulin G glycosylation in aging and diseases

I Gudelj, G Lauc, M Pezer - Cellular Immunology, 2018 - Elsevier
The Immunoglobulin G (IgG) glycome is well known for its heterogeneity and shows a significant
degree of variation within populations. IgG glycome composition is influenced both by …

[PDF][PDF] Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells

…, M Li, S Zhang, Y Liu, J Spurrier, L Zhang, I Gudelj… - Neuron, 2022 - cell.com
The hippocampal-entorhinal system supports cognitive functions, has lifelong neurogenic
capabilities in many species, and is selectively vulnerable to Alzheimer's disease. To …

[PDF][PDF] Association of systemic lupus erythematosus with decreased immunosuppressive potential of the IgG glycome

F Vučković, J Krištić, I Gudelj, M Teruel… - Arthritis & …, 2015 - Wiley Online Library
Objective Glycans attached to the Fc portion of IgG are important modulators of IgG effector
functions. Interindividual differences in IgG glycome composition are large and they …

[HTML][HTML] N-glycosylation and inflammation; the not-so-sweet relation

B Radovani, I Gudelj - Frontiers in Immunology, 2022 - frontiersin.org
Chronic inflammation is the main feature of many long-term inflammatory diseases such as
autoimmune diseases, metabolic disorders, and cancer. There is a growing number of …

Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases

…, T Keser, F Vučković, I Ugrina, J Krištić, I Gudelj… - Science …, 2020 - science.org
Effector functions of immunoglobulin G (IgG) are regulated by the composition of a glycan
moiety, thus affecting activity of the immune system. Aberrant glycosylation of IgG has been …

[HTML][HTML] Increased plasma N-glycome complexity is associated with higher risk of type 2 diabetes

…, F Vučković, N Selak, T Pavić, E Lukić, I Gudelj… - Diabetologia, 2017 - Springer
Aims/hypothesis Better understanding of type 2 diabetes and its prevention is a pressing need.
Changes in human plasma N-glycome are associated with many diseases and represent …

Glycosylation profile of immunoglobulin G is cross-sectionally associated with cardiovascular disease risk score and subclinical atherosclerosis in two independent …

C Menni, I Gudelj, E Macdonald-Dunlop… - Circulation …, 2018 - Am Heart Assoc
Rationale: One measure of protein glycosylation (GlycA) has been reported to predict higher
cardiovascular risk by reflecting inflammatory pathways. Objective: The main objective of …

[HTML][HTML] Low galactosylation of IgG associates with higher risk for future diagnosis of rheumatoid arthritis during 10 years of follow-up

I Gudelj, PP Salo, I Trbojević-Akmačić, M Albers… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Antibodies are known to have an important role in the development of rheumatoid arthritis (RA),
one of the most prevalent chronic inflammatory diseases which primarily involves the …

High-throughput glycomics: optimization of sample preparation

I Trbojević Akmačić, I Ugrina, J Štambuk, I Gudelj… - Biochemistry …, 2015 - Springer
Glycosylation affects structure, folding, and function of numerous proteins. Aberrant glycosylation
has been shown to be associated with different diseases. A wide range of analytical …

[HTML][HTML] Effects of environmental factors on severity and mortality of COVID-19

D Kifer, D Bugada, J Villar-Garcia, I Gudelj… - Frontiers in …, 2021 - frontiersin.org
Background: Most respiratory viruses show pronounced seasonality, but for SARS-CoV-2,
this still needs to be documented. Methods: We examined the disease progression of COVID-…