User profiles for Ivan Gudelj
Ivan GudeljAssistant Professor at Faculty of Biotechnology and Drug Development, University of Rijeka Verified email at uniri.hr Cited by 1977 |
[HTML][HTML] Immunoglobulin G glycosylation in aging and diseases
The Immunoglobulin G (IgG) glycome is well known for its heterogeneity and shows a significant
degree of variation within populations. IgG glycome composition is influenced both by …
degree of variation within populations. IgG glycome composition is influenced both by …
[PDF][PDF] Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells
The hippocampal-entorhinal system supports cognitive functions, has lifelong neurogenic
capabilities in many species, and is selectively vulnerable to Alzheimer's disease. To …
capabilities in many species, and is selectively vulnerable to Alzheimer's disease. To …
[PDF][PDF] Association of systemic lupus erythematosus with decreased immunosuppressive potential of the IgG glycome
Objective Glycans attached to the Fc portion of IgG are important modulators of IgG effector
functions. Interindividual differences in IgG glycome composition are large and they …
functions. Interindividual differences in IgG glycome composition are large and they …
[HTML][HTML] N-glycosylation and inflammation; the not-so-sweet relation
B Radovani, I Gudelj - Frontiers in Immunology, 2022 - frontiersin.org
Chronic inflammation is the main feature of many long-term inflammatory diseases such as
autoimmune diseases, metabolic disorders, and cancer. There is a growing number of …
autoimmune diseases, metabolic disorders, and cancer. There is a growing number of …
Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases
Effector functions of immunoglobulin G (IgG) are regulated by the composition of a glycan
moiety, thus affecting activity of the immune system. Aberrant glycosylation of IgG has been …
moiety, thus affecting activity of the immune system. Aberrant glycosylation of IgG has been …
[HTML][HTML] Increased plasma N-glycome complexity is associated with higher risk of type 2 diabetes
Aims/hypothesis Better understanding of type 2 diabetes and its prevention is a pressing need.
Changes in human plasma N-glycome are associated with many diseases and represent …
Changes in human plasma N-glycome are associated with many diseases and represent …
Glycosylation profile of immunoglobulin G is cross-sectionally associated with cardiovascular disease risk score and subclinical atherosclerosis in two independent …
Rationale: One measure of protein glycosylation (GlycA) has been reported to predict higher
cardiovascular risk by reflecting inflammatory pathways. Objective: The main objective of …
cardiovascular risk by reflecting inflammatory pathways. Objective: The main objective of …
[HTML][HTML] Low galactosylation of IgG associates with higher risk for future diagnosis of rheumatoid arthritis during 10 years of follow-up
I Gudelj, PP Salo, I Trbojević-Akmačić, M Albers… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Antibodies are known to have an important role in the development of rheumatoid arthritis (RA),
one of the most prevalent chronic inflammatory diseases which primarily involves the …
one of the most prevalent chronic inflammatory diseases which primarily involves the …
High-throughput glycomics: optimization of sample preparation
Glycosylation affects structure, folding, and function of numerous proteins. Aberrant glycosylation
has been shown to be associated with different diseases. A wide range of analytical …
has been shown to be associated with different diseases. A wide range of analytical …
[HTML][HTML] Effects of environmental factors on severity and mortality of COVID-19
Background: Most respiratory viruses show pronounced seasonality, but for SARS-CoV-2,
this still needs to be documented. Methods: We examined the disease progression of COVID-…
this still needs to be documented. Methods: We examined the disease progression of COVID-…