Background The burden of invasive pneumococcal disease in young children decreased
dramatically following introduction of the 7-valent pneumococcal conjugate vaccine (PCV7). …

Background Characterisation of risk groups who may benefit from pneumococcal vaccination
is essential for the generation of recommendations and policy. Methods We reviewed the …

Background . Precise etiologic diagnosis in pediatric community-acquired pneumonia (CAP)
remains challenging. Methods . We conducted a retrospective study of CAP etiology in 2 …

Introduction Assessment of the reflux–cough association in children is challenging. Esophageal
(impedance) pH recording is sensitive to recognize reflux. However, cough recorded by …

To better understand vaccine-induced protection and its potential failure in light of recent
whooping cough resurgence, we evaluated quantity as well as quality of memory T cell …

Background Young children with persistent wheezing pose a diagnostic and therapeutical
challenge to the pediatrician. We aimed to evaluate bacterial bronchial infection as a possible …

In children with persistent respiratory symptoms despite regular anti-asthma inhalation
treatment, diagnostic investigations to exclude underlying disease are warranted. 124 children …

Two CF patients developed Cushing's syndrome during administration of inhaled budesonide
(400 μg/d) with oral itraconazole in one and with clarithromycin in the other patient. …

Community-acquired pneumonia (CAP) is a major cause of morbidity in children. This study
estimated the proportion of children with pneumococcal CAP among children hospitalised …

Recently, a moderate increase in the prevalence of pertussis, possibly contracted from
adults, has been observed among unvaccinated children. During a 3-year period, we …