User profiles for I. Callebaut

Isabelle Callebaut

Centre National de la Recherche Scientifique, Université Pierre et Marie Curie
Verified email at impmc.upmc.fr
Cited by 21918

Deciphering protein sequence information through hydrophobic cluster analysis (HCA): current status and perspectives

I Callebaut, G Labesse, P Durand, A Poupon… - Cellular and Molecular …, 1997 - Springer
Ten years after the idea of hydrophobic cluster analysis (HCA) was conceived and first pub
lished, theoretical and practical experience has shown this unconventional method of protein …

Phylogenetic analysis and identification of pseudogenes reveal a progressive loss of zona pellucida genes during evolution of vertebrates

G Goudet, S Mugnier, I Callebaut… - Biology of …, 2008 - academic.oup.com
Vertebrate eggs are surrounded by an extracellular matrix with similar functions and conserved
individual components: the zona pellucida (ZP) glycoproteins. In mammals, chickens, …

Synthesis and reactivity of 2-(carboxymethyl) aziridine derivatives

G Callebaut, T Meiresonne, N De Kimpe… - Chemical …, 2014 - ACS Publications
More than a decade ago, the question was raised by Sweeney if aziridines are epoxides’
ugly cousins? 1 The overview on the biological properties, synthetic accessibility, and useful …

FlowSOM: Using self‐organizing maps for visualization and interpretation of cytometry data

S Van Gassen, B Callebaut, MJ Van Helden… - Cytometry Part …, 2015 - Wiley Online Library
The number of markers measured in both flow and mass cytometry keeps increasing steadily.
Although this provides a wealth of information, it becomes infeasible to analyze these …

[HTML][HTML] Artemis, a novel DNA double-strand break repair/V (D) J recombination protein, is mutated in human severe combined immune deficiency

D Moshous, I Callebaut, R De Chasseval, B Corneo… - Cell, 2001 - cell.com
The V(D)J recombination process insures the somatic diversification of immunoglobulin and
antigen T cell receptor encoding genes. This reaction is initiated by a DNA double-strand …

[HTML][HTML] Munc13-4 is essential for cytolytic granules fusion and is mutated in a form of familial hemophagocytic lymphohistiocytosis (FHL3)

J Feldmann, I Callebaut, G Raposo, S Certain, D Bacq… - Cell, 2003 - cell.com
Secretion of cytolytic granules content at the immunological synapse is a highly regulated
process essential for lymphocyte cytotoxicity. This process requires the rapid transfer of …

Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases.

B Henrissat, I Callebaut, S Fabrega… - Proceedings of the …, 1995 - National Acad Sciences
The regions surrounding the catalytic amino acids previously identified in a few "retaining" O-glycosyl
hydrolases (EC 3.2.1) have been analyzed by hydrophobic cluster analysis and …

Mutation in bone morphogenetic protein receptor-IB is associated with increased ovulation rate in Booroola Merino ewes

…, J Riquet, D Monniaux, I Callebaut… - Proceedings of the …, 2001 - National Acad Sciences
Ewes from the Booroola strain of Australian Mérino sheep are characterized by high ovulation
rate and litter size. This phenotype is due to the action of the FecB B allele of a major gene …

[HTML][HTML] From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair

I Callebaut, JP Mornon - FEBS letters, 1997 - Elsevier
Inherited mutations in BRCA1 predispose to breast and ovarian cancer, but the biological
function of the BRCA1 protein has remained largely elusive. The recent correspondence of …

Tenofovir alafenamide versus tenofovir disoproxil fumarate, coformulated with elvitegravir, cobicistat, and emtricitabine, for initial treatment of HIV-1 infection: two …

…, A Plummer, L Zhong, H Cao, H Martin, C Callebaut… - The Lancet, 2015 - thelancet.com
Background Tenofovir disoproxil fumarate can cause renal and bone toxic effects related to
high plasma tenofovir concentrations. Tenofovir alafenamide is a novel tenofovir prodrug …