[HTML][HTML] Adaptive servo-ventilation for central sleep apnea in systolic heart failure

MR Cowie, H Woehrle, K Wegscheider… - … England Journal of …, 2015 - Mass Medical Soc
Background Central sleep apnea is associated with poor prognosis and death in patients
with heart failure. Adaptive servo-ventilation is a therapy that uses a noninvasive ventilator to …

Clinical outcome endpoints in heart failure trials: a European Society of Cardiology Heart Failure Association consensus document

…, AA Voors, SM Wasserman, H Woehrle… - European journal of …, 2013 - Wiley Online Library
Endpoint selection is a critically important step in clinical trial design. It poses major challenges
for investigators, regulators, and study sponsors, and it also has important clinical and …

Prevalence and predictors of sleep-disordered breathing in patients with stable chronic heart failure: the SchlaHF registry

M Arzt, H Woehrle, O Oldenburg, A Graml, A Suling… - JACC: Heart Failure, 2016 - jacc.org
Holger WoehrleWoehrle and Graml are employees of ResMed. Dr. Oldenburg has acted
as a consultant for ResMed and Respicardia… Arzt and Woehrle contributed equally to this work. …

[HTML][HTML] Obstructive sleep apnea in women: specific issues and interventions

A Wimms, H Woehrle, S Ketheeswaran… - BioMed research …, 2016 - hindawi.com
Obstructive sleep apnea (OSA) has traditionally been seen as a male disease. However,
the importance of OSA in women is increasingly being recognized, along with a number of …

The importance of sleep-disordered breathing in cardiovascular disease

D Linz, H Woehrle, T Bitter, H Fox, MR Cowie… - Clinical Research in …, 2015 - Springer
Obstructive sleep apnoea and central sleep apnoea/Cheyne-Stokes respiration are
collectively referred to as sleep-disordered breathing (SDB). Rapidly accumulating evidence …

[HTML][HTML] Short-term CPAP adherence in obstructive sleep apnea: a big data analysis using real world data

PA Cistulli, J Armitstead, JL Pepin, H Woehrle… - Sleep …, 2019 - ncbi.nlm.nih.gov
1. Background Effective treatment of obstructive sleep apnea (OSA) is an important goal
due to its impact on quality of life, and the known cardiovascular and neurocognitive …

Cardiovascular outcomes with minute ventilation–targeted adaptive servo-ventilation therapy in heart failure: the CAT-HF trial

…, KJ Anstrom, AV Benjafield, H Woehrle… - Journal of the American …, 2017 - jacc.org
Background : Sleep apnea is common in hospitalized heart failure (HF) patients and is
associated with increased morbidity and mortality. Objectives : The CAT-HF (Cardiovascular …

Rationale and design of the SERVE‐HF study: treatment of sleep‐disordered breathing with predominant central sleep apnoea with adaptive servo‐ventilation in …

MR Cowie, H Woehrle, K Wegscheider… - European journal of …, 2013 - Wiley Online Library
Aims Central sleep apnoea/Cheyne–Stokes respiration (CSA/CSR) is a risk factor for increased
mortality and morbidity in heart failure (HF). Adaptive servo‐ventilation (ASV) is a non‐…

Management of continuous positive airway pressure treatment compliance using telemonitoring in obstructive sleep apnoea

C Turino, J de Batlle, H Woehrle… - European …, 2017 - Eur Respiratory Soc
Continuous positive airway pressure (CPAP) is an effective treatment for obstructive sleep
apnoea (OSA), but treatment compliance is often unsatisfactory. This study investigated the …

[HTML][HTML] Trajectories of emergent central sleep apnea during CPAP therapy

…, S Shao, A Malhotra, PA Cistulli, JL Pepin, H Woehrle - Chest, 2017 - Elsevier
Background The emergence of central sleep apnea (CSA) during positive airway pressure (PAP)
therapy has been observed clinically in approximately 10% of obstructive sleep apnea …