[HTML][HTML] The usefulness of monomeric periostin as a biomarker for idiopathic pulmonary fibrosis

…, N Sakamoto, K Takahashi, H Yamamoto, H Kushima… - PloS one, 2017 - journals.plos.org
The natural course of idiopathic pulmonary fibrosis (IPF) is variable. Predicting disease
progression and survival in IPF is important for treatment. We previously demonstrated that …

[HTML][HTML] Autopsy analyses in acute exacerbation of idiopathic pulmonary fibrosis

K Oda, H Ishimoto, S Yamada, H Kushima, H Ishii… - Respiratory …, 2014 - Springer
Background Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) is associated with
high mortality. However, few studies have so far reviewed analyses of autopsy findings in …

[HTML][HTML] Pleuroparenchymal fibroelastosis diagnosed by multidisciplinary discussions in Japan

H Ishii, K Watanabe, H Kushima, T Baba… - Respiratory …, 2018 - Elsevier
Background Pleuroparenchymal fibroelastosis (PPFE) is a rare subset of idiopathic interstitial
pneumonias. No large-scale clinical studies of PPFE have been published. The aim of the …

[HTML][HTML] A proposed prognostic prediction score for pleuroparenchymal fibroelastosis

…, T Miyamura, Y Ueda, Y Yoshida, H Kushima… - Respiratory …, 2021 - Springer
Background Clinical course of pleuroparenchymal fibroelastosis (PPFE) shows considerable
variation among patients, but there is no established prognostic prediction model for PPFE. …

Limited efficacy of nintedanib for idiopathic pleuroparenchymal fibroelastosis

…, T Ikeda, Y Ueda, Y Yoshida, H Kushima… - Respiratory …, 2022 - Elsevier
Hisako Kushima: data curation, writing–review and editing, and final approval of the
manuscript. Hiroshi Ishii: conceptualization, investigation, writing–review and editing, supervision, …

The serum KL‐6 levels in untreated idiopathic pulmonary fibrosis can naturally decline in association with disease progression

H Ishii, H Kushima, Y Kinoshita, M Fujita… - The Clinical …, 2018 - Wiley Online Library
Background Serum KL‐6 is known to be a useful biomarker for the diagnosis and assessment
of the disease activity in idiopathic pulmonary fibrosis (IPF). However, some patients with …

Pleuroparenchymal fibroelastosis as a histological background of autoimmune diseases

Y Kinoshita, K Watanabe, H Ishii, H Kushima… - Virchows Archiv, 2019 - Springer
Patients with autoimmune disease–related interstitial lung disease (AID-ILD) occasionally
develop radiologic pleuroparenchymal fibroelastosis (PPFE)–like lesions. However, the …

Proliferation of elastic fibres in idiopathic pulmonary fibrosis: a whole‐slide image analysis and comparison with pleuroparenchymal fibroelastosis

Y Kinoshita, K Watanabe, H Ishii, H Kushima… - …, 2017 - Wiley Online Library
Aims We occasionally encounter patients with idiopathic pulmonary fibrosis ( IPF ) who have
similar imaging patterns to those of pleuroparenchymal fibroelastosis ( PPFE ) in the upper …

The similarities and differences between pleuroparenchymal fibroelastosis and idiopathic pulmonary fibrosis

H Ishii, Y Kinoshita, H Kushima… - Chronic Respiratory …, 2019 - journals.sagepub.com
The idiopathic form of pleuroparenchymal fibroelastosis (PPFE) is categorized as a rare
idiopathic interstitial pneumonia in the current classification. The majority of PPFE cases are …

Cloning of the lanosterol 14-α-demethylase (ERG11) gene in Trichosporon asahii: a possible association between G453R amino acid substitution and azole …

H Kushima, I Tokimatsu, H Ishii, R Kawano… - FEMS yeast …, 2012 - academic.oup.com
Lanosterol 14-α-demethylase (Erg11 protein; Erg11p), encoded by the ERG11 gene, is the
primary target of azoles. Recently, a change in affinity of this enzyme for azoles has been …