Background Although several computer-aided computed tomography (CT) analysis methods
have been reported to objectively assess the disease severity and progression of idiopathic …

Rationale: Periostin is a matricellular protein that is involved in the pathophysiology of allergic
rhinitis, chronic rhinosinusitis, and asthma. Associations of serum periostin with systemic …

Background Asthmatic cough is often refractory to standard treatments such as inhaled
corticosteroids (ICS) and long-acting β 2 agonists (LABA). Tiotropium may modulate cough reflex …

Computed tomography (CT) assessment of the cross-sectional area of the erector spinae
muscles (ESM CSA ) can be used to evaluate sarcopenia and cachexia in patients with lung …

Rationale: Capsaicin cough reflex sensitivity (C-CS) is associated with poorly controlled
asthma, although its association with severe asthma remains unknown. Objectives: To …

Background: While gastroesophageal reflux disease (GERD) is one of the commonest causes
of subacute/chronic cough along with cough-variant asthma (CVA) and rhinosinusitis, its …

Background The serum creatinine/cystatin C (Cr/CysC) ratio has attracted attention as a
marker for sarcopenia, but has not been studied in patients with idiopathic pulmonary fibrosis (…

… Author links open overlay panel Hirotsugu Ohkubo a , Hiroaki Nakagawa b , Akio Niimi a …
Ohkubo et al. [33] investigated the normally attenuated lung volume percentage, defined …

External stimuli such as cigarette smoke and house dust mite are often involved in the
development and exacerbation of asthma. These risk factors could activate or sensitize transient …

Objectives Sarcopenia is a syndrome characterized by reduced muscle mass and function.
It is well-recognized as a complication in chronic diseases such as chronic obstructive …