User profiles for Helder Novais e Bastos

Helder Bastos

- Verified email at letras.up.pt - Cited by 1506

Helder Novais e Bastos

- Verified email at med.up.pt - Cited by 581

Impact of Azathioprine use in chronic hypersensitivity pneumonitis patients

…, S Raimundo, N Melo, PC Mota, HN e Bastos… - Pulmonary …, 2020 - Elsevier
Introduction Systemic corticosteroids are widely used in chronic hypersensitivity pneumonitis
(CHP); however, there is not much evidence to support their use, besides being associated …

[HTML][HTML] Role of bronchoscopic techniques in the diagnosis of thoracic sarcoidosis

C Pedro, N Melo, H Novais e Bastos… - Journal of Clinical …, 2019 - mdpi.com
The diagnosis of sarcoidosis relies on clinical and radiological presentation, evidence of
non-caseating granulomas in histopathology and exclusion of alternative causes of …

[HTML][HTML] Pulmonary emphysema regional distribution and extent assessed by chest computed tomography is associated with pulmonary function impairment in …

P Gomes, HN Bastos, A Carvalho, A Lobo… - Frontiers in …, 2021 - frontiersin.org
Objective: This study aimed to evaluate how emphysema extent and its regional distribution
quantified by chest CT are associated with clinical and functional severity in patients with …

Diagnostic yield and safety of transbronchial lung cryobiopsy and surgical lung biopsy in interstitial lung diseases: a systematic review and meta-analysis

…, F Machado, A Morais, HN Bastos - European …, 2022 - Eur Respiratory Soc
Introduction: Transbronchial lung cryobiopsy (TBLC) is increasingly being used as an alternative
to video-assisted thoracoscopic surgery (VATS) biopsy to establish the histopathologic …

[HTML][HTML] Mycobacterium tuberculosis associated with severe tuberculosis evades cytosolic surveillance systems and modulates IL-1β production

…, AG Castro, JT Guimarães, HN Bastos… - Nature …, 2020 - nature.com
Genetic diversity of Mycobacterium tuberculosis affects immune responses and clinical
outcomes of tuberculosis (TB). However, how bacterial diversity orchestrates immune responses …

Association of polymorphisms in genes of the homologous recombination DNA repair pathway and thyroid cancer risk

HN Bastos, MR Antao, SN Silva, AP Azevedo, I Manita… - Thyroid, 2009 - liebertpub.com
Background: Ionizing radiation exposure has been pointed out as a risk factor for thyroid
cancer. The double-strand breaks induced by this carcinogen are usually repaired by …

[HTML][HTML] A prediction rule to stratify mortality risk of patients with pulmonary tuberculosis

HN Bastos, NS Osório, AG Castro, A Ramos… - PLoS …, 2016 - journals.plos.org
Tuberculosis imposes high human and economic tolls, including in Europe. This study was
conducted to develop a severity assessment tool for stratifying mortality risk in pulmonary …

Mortality risk prediction with ILD-GAP index in a fibrotic hypersensitivity pneumonitis cohort

…, B Lima, I Neves, H Novais-Bastos… - Therapeutic …, 2022 - journals.sagepub.com
Background: Fibrotic hypersensitivity pneumonitis (fHP) is associated with significant morbidity
and mortality. Interstitial lung disease–gender-age-physiology (ILD-GAP) performance in …

Insights on chronic hypersensitivity pneumonitis' treatment: Factors associated with a favourable response to azathioprine

…, N Melo, PC Mota, O Sokhatska, HN Bastos… - Life Sciences, 2021 - Elsevier
Background The use of immunosuppressive and antifibrotic agents for the treatment of
chronic hypersensitivity pneumonitis (CHP) appears promising, but there is still no evidence …

[HTML][HTML] Predictors of survival and technical success of bronchoscopic interventions in malignant airway obstruction

…, S Saleiro, AP Vaz, H Novais-Bastos… - Journal of Thoracic …, 2021 - ncbi.nlm.nih.gov
Background Malignant airway obstruction (MAO) leads to quality of life impairment and
increased mortality. Interventional bronchoscopy allows airway patency restoring, leading to a …