Endothelial hyperpermeability induced by inflammatory mediators is a hallmark of sepsis
and adult respiratory distress syndrome. Increased levels of the regulatory peptide …

In 49 acute respiratory distress syndrome (ARDS) patients, the phenotype of alveolar
macrophages (AMs) was analyzed by flow cytometry. Bronchoalveolar lavage (BAL) was …

Objectives: Community-acquired pneumonia is a very common infectious disease associated
with significant morbidity and mortality. Streptococcus pneumoniae is the predominant …

CAPNETZ, ein vom Bundesministerium für Bildung und Forschung (BMBF) gefördertes
Medizinisches Kompetenznetzwerk, hat das Thema „ambulant erworbene Pneumonie“ (CAP) in …

The pleiotropic cytokine tumor necrosis factor-α (TNF-α) and thrombin lead to increased
endothelial permeability in sepsis. Numerous studies demonstrated the significance of …

Objective: Acute respiratory failure is a significant complication of severe pneumococcal
pneumonia. In a mouse model, we observed early-onset lung microvascular leakage after …

Objective To determine differences in aetiologies, initial antimicrobial treatment choices and
outcomes in patients with nursing-home-acquired pneumonia (NHAP) compared with …

Objectives We aimed to explore the association between vitamin D levels and the severity,
mortality and microbiological etiology of community-acquired pneumonia. Methods Vitamin D …

Background Early organ dysfunction determines the prognosis of community-acquired
pneumonia (CAP), and recognition of CAP as a medical emergency has been advocated. …

Community-acquired pneumonia (CAP) is associated with high morbidity and mortality, and
Streptococcus pneumoniae is the most prevalent causal pathogen identified in CAP. …