STUDY QUESTION Does chemotherapy exposure (with or without alkylating agents) or
primary diagnosis affect spermatogonial quantity in human prepubertal testicular tissue? …

DNA immunoprecipitation followed by sequencing (DIP-seq) is a common enrichment
method for profiling DNA modifications in mammalian genomes. However, the results of …

Pediatric T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy resulting
from overproduction of immature T-cells in the thymus and is typified by widespread …

OBJECTIVE: Preterm birth is associated with respiratory morbidity later in life, including
asthma. Previous studies have mainly focused on asthma in early childhood in children born …

Of late, decrease in mineral oil supplies has stimulated research on use of biomass as an
alternative energy source. Climate change has brought problems such as increased drought …

PURPOSE Several studies have indicated that broad genomic characterization of childhood
cancer provides diagnostically and/or therapeutically relevant information in selected high-…

Fertility preservation for male childhood cancer survivors not yet capable of producing
mature spermatozoa, relies on experimental approaches such as testicular explant culture. …

BACKGROUND AND OBJECTIVES: Childhood immunization may influence the
development of asthma, possibly due to lack of infections or a shift in the T-helper cell type 1/T-helper …

Background Studies of asthma in migrant populations illustrate the effects of environmental
changes. Objective In this register study we investigated the importance of exposure to a …

The beta-actin gene encodes 1 of 6 different actin proteins. De novo heterozygous missense
mutations in ACTB have been identified in patients with Baraitser-Winter syndrome (BRWS) …