Tumor-intrinsic PD-L1 signals regulate cell growth, pathogenesis, and autophagy in ovarian cancer and melanoma
PD-L1 antibodies produce efficacious clinical responses in diverse human cancers, but the
basis for their effects remains unclear, leaving a gap in the understanding of how to rationally …
basis for their effects remains unclear, leaving a gap in the understanding of how to rationally …
[HTML][HTML] Tumor cell-intrinsic PD-L1 promotes tumor-initiating cell generation and functions in melanoma and ovarian cancer
As tumor PD-L1 provides signals to anti-tumor PD-1+ T cells that blunt their functions, αPD-1
and αPD-L1 antibodies have been developed as anti-cancer immunotherapies based on …
and αPD-L1 antibodies have been developed as anti-cancer immunotherapies based on …
Significance of nutrition in pulmonary tuberculosis
S Kant, H Gupta, S Ahluwalia - Critical reviews in food science and …, 2015 - Taylor & Francis
Malnutrition and tuberculosis are both problems mostly of the developing countries. Tuberculosis
can lead to malnutrition and malnutrition may predispose to tuberculosis. Poor nutrition …
can lead to malnutrition and malnutrition may predispose to tuberculosis. Poor nutrition …
LPC and LPCC method of feature extraction in Speech Recognition System
H Gupta, D Gupta - … conference-cloud system and big data …, 2016 - ieeexplore.ieee.org
Automatic speech recognition (ASR) has been under the scrutiny of researchers for many
years. Speech Recognition System is the ability to listen what we speak, interpreter and …
years. Speech Recognition System is the ability to listen what we speak, interpreter and …
Adipose PD-L1 modulates PD-1/PD-L1 checkpoint blockade immunotherapy efficacy in breast cancer
Programmed death-ligand 1 (PD-L1) and its receptor programmed cell death protein 1 (PD-1)
modulate antitumor immunity and are major targets of checkpoint blockade immunotherapy…
modulate antitumor immunity and are major targets of checkpoint blockade immunotherapy…
Multimedia tool as a predictor for social media advertising-a YouTube way
Multimedia has embraced the marketing industry with its innovative tools. Advertising as a
part of marketing is not an exception. Social media is one of its tools which is growing with an …
part of marketing is not an exception. Social media is one of its tools which is growing with an …
[PDF][PDF] Design Continuums and the Path Toward Self-Designing Key-Value Stores that Know and Learn.
We introduce the concept of design continuums for the data layout of key-value stores. A
design continuum unifies major distinct data structure designs under the same model. The …
design continuum unifies major distinct data structure designs under the same model. The …
Bladder cancer cell‐intrinsic PD‐L1 signals promote mTOR and autophagy activation that can be inhibited to improve cytotoxic chemotherapy
Tumor cell‐intrinsic programmed death‐ligand 1 (PD‐L1) signals mediate immunopathologic
effects in breast, colon, and ovarian cancers and in melanomas, but bladder cancer (BC) …
effects in breast, colon, and ovarian cancers and in melanomas, but bladder cancer (BC) …
Tumor cell-intrinsic CD274/PD-L1: A novel metabolic balancing act with clinical potential
Tumor expression of the immune co-signaling molecule CD274/PD-L1 was originally described
as impeding antitumor immunity by direct engagement of its receptor, PDCD1/PD-1, on …
as impeding antitumor immunity by direct engagement of its receptor, PDCD1/PD-1, on …
CD122-Selective IL2 complexes reduce immunosuppression, promote Treg fragility, and sensitize tumor response to PD-L1 blockade
…, W Chen, JR Conejo-Garcia, V Hurez, H Gupta… - Cancer research, 2020 - AACR
These findings present CD122-targeted IL2 complexes as an advancement in cancer
immunotherapy, as they reduce Treg immunosuppression, improve anticancer immunity, and …
immunotherapy, as they reduce Treg immunosuppression, improve anticancer immunity, and …