User profiles for H.J. Zar

heather zar

Professor & Chair, Department of Paediatrics and Director of the MRC Unit on Child & …
Verified email at uct.ac.za
Cited by 56240

[HTML][HTML] Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a …

…, W Watthanaworawit, LM Yoshida, H Yu, HJ Zar… - The Lancet, 2017 - thelancet.com
Background We have previously estimated that respiratory syncytial virus (RSV) was associated
with 22% of all episodes of (severe) acute lower respiratory infection (ALRI) resulting in …

After asthma: redefining airways diseases

…, FD Martinez, PD Sly, E von Mutius, S Wenzel, HJ Zar… - The Lancet, 2018 - thelancet.com
Asthma is responsible for considerable global morbidity and health-care costs. Substantial
progress was made against key outcomes such as hospital admissions with asthma and …

Respiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape

…, J Wildenbeest, D Wiseman, HJ Zar… - The Lancet Infectious …, 2023 - thelancet.com
Respiratory syncytial virus is the second most common cause of infant mortality and a major
cause of morbidity and mortality in older adults (aged >60 years). Efforts to develop a …

Global strategy for asthma management and prevention: GINA executive summary

…, SD Sullivan, SE Wenzel, HJ Zar - European …, 2008 - Eur Respiratory Soc
Asthma is a serious health problem throughout the world. During the past two decades, many
scientific advances have improved our understanding of asthma and ability to manage and …

[HTML][HTML] Bivalent prefusion F vaccine in pregnancy to prevent RSV illness in infants

…, B Tapiero, RT Stein, FP Polack, HJ Zar… - … England Journal of …, 2023 - Mass Medical Soc
Background Whether vaccination during pregnancy could reduce the burden of respiratory
syncytial virus (RSV)–associated lower respiratory tract illness in newborns and infants is …

[HTML][HTML] Nirsevimab for prevention of RSV in healthy late-preterm and term infants

…, M Bosheva, SA Madhi, WJ Muller, HJ Zar… - … England Journal of …, 2022 - Mass Medical Soc
Background Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract
infection and hospitalization in infants. Nirsevimab is a monoclonal antibody to the RSV fusion …

Induced sputum versus gastric lavage for microbiological confirmation of pulmonary tuberculosis in infants and young children: a prospective study

HJ Zar, D Hanslo, P Apolles, G Swingler, G Hussey - The Lancet, 2005 - thelancet.com
… Heather Zar and colleagues report the results of a prospective study in Cape Town,
South Africa, in which they compared induced sputum and gastric lavage for microbiological …

Diverse Pseudomonas aeruginosa gene products stimulate respiratory epithelial cells to produce interleukin-8.

E DiMango, HJ Zar, R Bryan… - The Journal of clinical …, 1995 - Am Soc Clin Investig
Respiratory epithelial cells play a crucial role in the inflammatory response during
Pseudomonas aeruginosa infection in the lungs of patients with cystic fibrosis. In this study, we …

[HTML][HTML] Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years …

…, D Wurzel, LM Yoshida, CF Yung, HJ Zar… - The Lancet, 2022 - thelancet.com
Background Respiratory syncytial virus (RSV) is the most common cause of acute lower
respiratory infection in young children. We previously estimated that in 2015, 33·1 million …

[HTML][HTML] Accuracy of the Xpert MTB/RIF test for the diagnosis of pulmonary tuberculosis in children admitted to hospital in Cape Town, South Africa: a descriptive study

…, B Eley, CC Boehme, W Zemanay, HJ Zar - The Lancet infectious …, 2011 - thelancet.com
Background WHO recommends that Xpert MTB/RIF replaces smear microscopy for initial
diagnosis of suspected HIV-associated tuberculosis or multidrug-resistant pulmonary …