User profiles for H. Cabral

Horacio Cabral

Associate Professor, Department of Bioengineering, The University of Tokyo
Verified email at bmw.tu-tokyo.ac.jp
Cited by 15042

Block copolymer micelles in nanomedicine applications

H Cabral, K Miyata, K Osada, K Kataoka - Chemical reviews, 2018 - ACS Publications
Polymeric micelles are demonstrating high potential as nanomedicines capable of controlling
the distribution and function of loaded bioactive agents in the body, effectively overcoming …

Progress of drug-loaded polymeric micelles into clinical studies

H Cabral, K Kataoka - Journal of Controlled Release, 2014 - Elsevier
h ml − 1 , while for irinotecan at 66.7 mg kg − 1 the AUC was 0.022 μg h ml − 1, and 0.001 μg
h … SN-38 was rapidly cleared 1 h after injection, while NK012 was detected for more than 96 …

Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges

JD Martin, H Cabral, T Stylianopoulos… - Nature reviews Clinical …, 2020 - nature.com
Multiple nanotherapeutics have been approved for patients with cancer, but their effects on
survival have been modest and, in some examples, less than those of other approved …

[HTML][HTML] The body-mass index, airflow obstruction, dyspnea, and exercise capacity index in chronic obstructive pulmonary disease

…, RA Mendez, V Pinto Plata, HJ Cabral - … England Journal of …, 2004 - Mass Medical Soc
Background Chronic obstructive pulmonary disease (COPD) is characterized by an incompletely
reversible limitation in airflow. A physiological variable — the forced expiratory volume …

Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size

H Cabral, Y Matsumoto, K Mizuno, Q Chen… - Nature …, 2011 - nature.com
… d, Micelles of all sizes incubated in cell culture media containing 10% serum at 37 C
maintained their sizes over 48 h. e, Plasma clearances of micelles with different diameters follow …

Effects of maternal marijuana and cocaine use on fetal growth

…, H Cabral, R Timperi, H Bauchner - … England Journal of …, 1989 - Mass Medical Soc
To investigate the effects on infants of the use of marijuana and cocaine during pregnancy
and to compare the importance of urine assays with that of interviews in ascertaining drug use…

Tight glycemic control in diabetic coronary artery bypass graft patients improves perioperative outcomes and decreases recurrent ischemic events

HL Lazar, SR Chipkin, CA Fitzgerald, Y Bao, H Cabral… - Circulation, 2004 - Am Heart Assoc
Background— This study sought to determine whether tight glycemic control with a modified
glucose-insulin-potassium (GIK) solution in diabetic coronary artery bypass graft (CABG) …

The 6‐min walk distance: change over time and value as a predictor of survival in severe COPD

VM Pinto-Plata, C Cote, H Cabral… - European Respiratory …, 2004 - Eur Respiratory Soc
The 6‐min walk distance (6MWD) is used to evaluate the functional capacity of patients with
chronic obstructive pulmonary disease (COPD). The change in 6MWD over time and its …

Depressive symptoms during pregnancy: relationship to poor health behaviors

…, H Amaro, H Bauchner, H Cabral - American journal of …, 1989 - Elsevier
Although depression is well studied in women, little information is available regarding
depression during pregnancy. The purpose of this study was to determine the correlates of …

Violence during pregnancy and substance use.

H Amaro, LE Fried, H Cabral… - American journal of …, 1990 - ajph.aphapublications.org
Violent incidents were assessed as part of a prospective study of 1,243 pregnant women.
Participants were predominantly poor, urban, minority group women. Seven percent (n = 92) of …